Difference between revisions of "Cofactors"

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(Manganese)
(Zinc)
 
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Line 20: Line 20:
 
* [[TyrA]]
 
* [[TyrA]]
 
* [[YcbD]]
 
* [[YcbD]]
 +
* [[YycR]]
  
 
= NADP<sup>+</sup> =
 
= NADP<sup>+</sup> =
Line 40: Line 41:
 
* [[YqkF]]
 
* [[YqkF]]
 
* [[YtsJ]]
 
* [[YtsJ]]
 +
* [[YugJ]]
 
* [[YvgN]]
 
* [[YvgN]]
  
Line 65: Line 67:
 
* [[NasB]]
 
* [[NasB]]
 
* [[NasD]]
 
* [[NasD]]
 +
* [[Nox]]
 
* [[PdhD]]
 
* [[PdhD]]
 
* [[PucC]]
 
* [[PucC]]
Line 96: Line 99:
  
 
= FMN =
 
= FMN =
 +
* [[CmoJ]]
 +
* [[CmoO]]
 
* [[CysJ]]
 
* [[CysJ]]
 +
* [[DusB1]]
 +
* [[DusB2]]
 
* [[GltA]]
 
* [[GltA]]
 
* [[HypO]]
 
* [[HypO]]
Line 102: Line 109:
 
* [[YqjM]]
 
* [[YqjM]]
 
* [[YtvA]]
 
* [[YtvA]]
 +
* [[YxeK]]
  
 
= Additional Flavoproteins =
 
= Additional Flavoproteins =
Line 135: Line 143:
 
* [[YqeM]]
 
* [[YqeM]]
 
* [[YqxC]]
 
* [[YqxC]]
 +
 +
= Menachinone =
 +
* [[ForC1]]
 +
* [[ForC2]]
  
 
= Biotin =
 
= Biotin =
Line 148: Line 160:
  
 
= Copper =
 
= Copper =
 +
* [[CotA]]
 
* [[CtaC]] (Cu(A))
 
* [[CtaC]] (Cu(A))
 
* [[CtaD]] (Cu(B))
 
* [[CtaD]] (Cu(B))
 
* [[QoxB]] (Cu(B))
 
* [[QoxB]] (Cu(B))
 
* [[Sco]]
 
* [[Sco]]
 +
 +
 +
----
 +
= Ammonium =
 +
* [[CoaX]]
  
 
= Nickel =
 
= Nickel =
 +
* [[YugJ]]
 
* [[UreA]]-[[UreB]]-[[UreC]] (urease), the nickel ion binds the active site in [[UreC]]
 
* [[UreA]]-[[UreB]]-[[UreC]] (urease), the nickel ion binds the active site in [[UreC]]
 
<pubmed> 19363030 23539618 20442959 </pubmed>
 
<pubmed> 19363030 23539618 20442959 </pubmed>
  
 
= Magnesium=
 
= Magnesium=
 +
* [[DesK]]
 +
* [[EngA]]
 
* [[ExoR]]
 
* [[ExoR]]
 
* [[FosB]]
 
* [[FosB]]
Line 165: Line 186:
 
* [[YwpJ]]
 
* [[YwpJ]]
 
* [[RnhB]]
 
* [[RnhB]]
 +
* [[RsbU]]
 
* [[TagT]]
 
* [[TagT]]
 
* [[TagU]]
 
* [[TagU]]
Line 177: Line 199:
 
* [[DisA]]
 
* [[DisA]]
 
* [[LplD]]
 
* [[LplD]]
 +
* [[LtaS]]
 
* [[MelA]]
 
* [[MelA]]
 
* [[MutT]]
 
* [[MutT]]
Line 187: Line 210:
 
* [[RnhB]]
 
* [[RnhB]]
 
* [[RnhC]]
 
* [[RnhC]]
 +
* [[RocB]]
 
* [[RocF]]
 
* [[RocF]]
 +
* [[RsbU]]
 
* [[SpoIIE]]
 
* [[SpoIIE]]
 +
* [[YerA]]
 
* [[YhfI]]
 
* [[YhfI]]
 +
* [[YisK]]
 +
* [[YloC]]
 
* [[YpgQ]]
 
* [[YpgQ]]
 
* [[YvcI]]
 
* [[YvcI]]
Line 200: Line 228:
 
* [[ComFB]]
 
* [[ComFB]]
 
* [[CsfB]]
 
* [[CsfB]]
 +
* [[FakA]]
 
* [[LdcB]]
 
* [[LdcB]]
 
* [[RpmE]]
 
* [[RpmE]]
Line 205: Line 234:
 
* [[RpmGB]]
 
* [[RpmGB]]
 
* [[RpsN]]
 
* [[RpsN]]
 +
* [[RtpA]]
 +
* [[SpoIVFB]]
 
* [[SufU]]
 
* [[SufU]]
 
* [[YbgG]]
 
* [[YbgG]]
 
* [[YitJ]]
 
* [[YitJ]]
 
* [[YqgT]]
 
* [[YqgT]]
 +
* [[YycR]]
  
 
= MoCo (molybdenum cofactor, molybdopterin) =
 
= MoCo (molybdenum cofactor, molybdopterin) =
 +
* [[ForC1]]
 +
* [[ForC2]]
 
* [[NarG]]
 
* [[NarG]]
 
* [[NasC]]
 
* [[NasC]]
Line 222: Line 256:
 
* [[Fer]]
 
* [[Fer]]
 
* [[Fnr]]
 
* [[Fnr]]
 +
* [[ForC1]]
 +
* [[ForC2]]
 
* [[GltA]]
 
* [[GltA]]
 
* [[GltB]]
 
* [[GltB]]
Line 267: Line 303:
  
 
==[2 Fe-2 S] cluster==
 
==[2 Fe-2 S] cluster==
* [[YjgC]]
+
* [[ForC1]]
 +
* [[ForC2]]
 
* [[YoaE]]
 
* [[YoaE]]
 
* [[YyaE]]
 
* [[YyaE]]
 
* [[YydG]]
 
* [[YydG]]
 
* [[YhfW]]
 
* [[YhfW]]
* [[YrhE]]
 
 
* [[YfkA]]
 
* [[YfkA]]
 
* [[YtqA]]
 
* [[YtqA]]
Line 299: Line 335:
  
 
= Thiamine pyrophosphate, TPP =
 
= Thiamine pyrophosphate, TPP =
* [[Tkt]]
+
* [[AcoA]]
 
* [[AlsS]]
 
* [[AlsS]]
 
+
* [[BkdAA]]
=== E1 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase ===
+
* [[Dxs]]
 +
* [[IlvB]]
 +
* [[IolD]]
 +
* [[OdhA]]
 
* [[PdhA]]
 
* [[PdhA]]
 +
* [[Tkt]]
 +
* [[YdaP]]
  
 
= Lipoic acid =
 
= Lipoic acid =

Latest revision as of 09:32, 30 October 2024

NAD+

NADP+

FAD

FMN

Additional Flavoproteins

Peter Macheroux, Barbara Kappes, Steven E Ealick
Flavogenomics--a genomic and structural view of flavin-dependent proteins.
FEBS J: 2011, 278(15);2625-34
[PubMed:21635694] [WorldCat.org] [DOI] (I p)


S-adenosyl-L-methionine (SAM)

Menachinone

Biotin

Cobalamin

Calcium

Copper



Ammonium

Nickel

Mark A Farrugia, Lee Macomber, Robert P Hausinger
Biosynthesis of the urease metallocenter.
J Biol Chem: 2013, 288(19);13178-85
[PubMed:23539618] [WorldCat.org] [DOI] (I p)

Harini Kaluarachchi, Kim C Chan Chung, Deborah B Zamble
Microbial nickel proteins.
Nat Prod Rep: 2010, 27(5);681-94
[PubMed:20442959] [WorldCat.org] [DOI] (I p)

Stephen W Ragsdale
Nickel-based Enzyme Systems.
J Biol Chem: 2009, 284(28);18571-5
[PubMed:19363030] [WorldCat.org] [DOI] (P p)


Magnesium

Manganese

dimanganic-tyrosyl radical cofactor

Zinc

MoCo (molybdenum cofactor, molybdopterin)

Iron-sulfur cluster

[2 Fe-2 S] cluster

Heme A

Heme b

Heme d

Protoheme IX

Heme (unspecified )

Thiamine pyrophosphate, TPP

Lipoic acid

E2 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase

H protein of the glycine cleavage system

  • GcvH (also required for LipL-catalyzed octanoyl transfer from AcpA to the E2s)

Pyridoxyl phosphate, PLP

Björn Richts, Jonathan Rosenberg, Fabian M Commichau
##Title##
Front Mol Biosci: 2019, 6;32
[PubMed:31134210] [WorldCat.org] [DOI] (P e)


Tetrahydrofalate

Methylene-THF