Difference between revisions of "Cofactors"
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Line 15: | Line 15: | ||
* [[MelA]] | * [[MelA]] | ||
* [[NasE]] | * [[NasE]] | ||
+ | * [[NtdC]] | ||
* [[RhaEW]] | * [[RhaEW]] | ||
* [[Tdh]] | * [[Tdh]] | ||
* [[TyrA]] | * [[TyrA]] | ||
* [[YcbD]] | * [[YcbD]] | ||
+ | * [[YycR]] | ||
= NADP<sup>+</sup> = | = NADP<sup>+</sup> = | ||
Line 33: | Line 35: | ||
* [[ProI]] | * [[ProI]] | ||
* [[QueF]] | * [[QueF]] | ||
+ | * [[YhdA]] | ||
* [[YhdN]] | * [[YhdN]] | ||
* [[YhfP]] | * [[YhfP]] | ||
Line 38: | Line 41: | ||
* [[YqkF]] | * [[YqkF]] | ||
* [[YtsJ]] | * [[YtsJ]] | ||
+ | * [[YugJ]] | ||
* [[YvgN]] | * [[YvgN]] | ||
Line 54: | Line 58: | ||
* [[GidA]] | * [[GidA]] | ||
* [[GlpD]] | * [[GlpD]] | ||
− | |||
* [[HemY]] | * [[HemY]] | ||
* [[Hmp]] | * [[Hmp]] | ||
Line 64: | Line 67: | ||
* [[NasB]] | * [[NasB]] | ||
* [[NasD]] | * [[NasD]] | ||
+ | * [[Nox]] | ||
* [[PdhD]] | * [[PdhD]] | ||
* [[PucC]] | * [[PucC]] | ||
Line 95: | Line 99: | ||
= FMN = | = FMN = | ||
+ | * [[CmoJ]] | ||
+ | * [[CmoO]] | ||
* [[CysJ]] | * [[CysJ]] | ||
+ | * [[DusB1]] | ||
+ | * [[DusB2]] | ||
+ | * [[GltA]] | ||
* [[HypO]] | * [[HypO]] | ||
* [[PyrD]] | * [[PyrD]] | ||
* [[YqjM]] | * [[YqjM]] | ||
* [[YtvA]] | * [[YtvA]] | ||
+ | * [[YxeK]] | ||
= Additional Flavoproteins = | = Additional Flavoproteins = | ||
Line 133: | Line 143: | ||
* [[YqeM]] | * [[YqeM]] | ||
* [[YqxC]] | * [[YqxC]] | ||
+ | |||
+ | = Menachinone = | ||
+ | * [[ForC1]] | ||
+ | * [[ForC2]] | ||
= Biotin = | = Biotin = | ||
Line 146: | Line 160: | ||
= Copper = | = Copper = | ||
+ | * [[CotA]] | ||
* [[CtaC]] (Cu(A)) | * [[CtaC]] (Cu(A)) | ||
* [[CtaD]] (Cu(B)) | * [[CtaD]] (Cu(B)) | ||
* [[QoxB]] (Cu(B)) | * [[QoxB]] (Cu(B)) | ||
* [[Sco]] | * [[Sco]] | ||
+ | |||
+ | |||
+ | ---- | ||
+ | = Ammonium = | ||
+ | * [[CoaX]] | ||
= Nickel = | = Nickel = | ||
+ | * [[YugJ]] | ||
* [[UreA]]-[[UreB]]-[[UreC]] (urease), the nickel ion binds the active site in [[UreC]] | * [[UreA]]-[[UreB]]-[[UreC]] (urease), the nickel ion binds the active site in [[UreC]] | ||
<pubmed> 19363030 23539618 20442959 </pubmed> | <pubmed> 19363030 23539618 20442959 </pubmed> | ||
= Magnesium= | = Magnesium= | ||
+ | * [[DesK]] | ||
+ | * [[EngA]] | ||
* [[ExoR]] | * [[ExoR]] | ||
* [[FosB]] | * [[FosB]] | ||
* [[HutP]] | * [[HutP]] | ||
+ | * [[KtrA]] | ||
* [[MrfB]] | * [[MrfB]] | ||
* [[YwpJ]] | * [[YwpJ]] | ||
* [[RnhB]] | * [[RnhB]] | ||
+ | * [[RsbU]] | ||
* [[TagT]] | * [[TagT]] | ||
* [[TagU]] | * [[TagU]] | ||
Line 170: | Line 195: | ||
* [[AlsS]] | * [[AlsS]] | ||
* [[CdaA]] | * [[CdaA]] | ||
+ | * [[ComEC]] | ||
* [[CotH]] | * [[CotH]] | ||
* [[DisA]] | * [[DisA]] | ||
* [[LplD]] | * [[LplD]] | ||
+ | * [[LtaS]] | ||
* [[MelA]] | * [[MelA]] | ||
* [[MutT]] | * [[MutT]] | ||
Line 183: | Line 210: | ||
* [[RnhB]] | * [[RnhB]] | ||
* [[RnhC]] | * [[RnhC]] | ||
+ | * [[RocB]] | ||
+ | * [[RocF]] | ||
+ | * [[RsbU]] | ||
* [[SpoIIE]] | * [[SpoIIE]] | ||
+ | * [[YerA]] | ||
* [[YhfI]] | * [[YhfI]] | ||
+ | * [[YisK]] | ||
+ | * [[YloC]] | ||
* [[YpgQ]] | * [[YpgQ]] | ||
* [[YvcI]] | * [[YvcI]] | ||
Line 195: | Line 228: | ||
* [[ComFB]] | * [[ComFB]] | ||
* [[CsfB]] | * [[CsfB]] | ||
+ | * [[FakA]] | ||
* [[LdcB]] | * [[LdcB]] | ||
* [[RpmE]] | * [[RpmE]] | ||
Line 200: | Line 234: | ||
* [[RpmGB]] | * [[RpmGB]] | ||
* [[RpsN]] | * [[RpsN]] | ||
+ | * [[RtpA]] | ||
+ | * [[SpoIVFB]] | ||
* [[SufU]] | * [[SufU]] | ||
* [[YbgG]] | * [[YbgG]] | ||
* [[YitJ]] | * [[YitJ]] | ||
* [[YqgT]] | * [[YqgT]] | ||
+ | * [[YycR]] | ||
= MoCo (molybdenum cofactor, molybdopterin) = | = MoCo (molybdenum cofactor, molybdopterin) = | ||
+ | * [[ForC1]] | ||
+ | * [[ForC2]] | ||
* [[NarG]] | * [[NarG]] | ||
* [[NasC]] | * [[NasC]] | ||
= Iron-sulfur cluster = | = Iron-sulfur cluster = | ||
+ | * [[AddB]] | ||
+ | * [[AlbA]] | ||
+ | * [[BioB]] | ||
* [[CitB]] | * [[CitB]] | ||
− | |||
− | |||
− | |||
− | |||
* [[CysI]] | * [[CysI]] | ||
+ | * [[Fer]] | ||
+ | * [[Fnr]] | ||
+ | * [[ForC1]] | ||
+ | * [[ForC2]] | ||
+ | * [[GltA]] | ||
+ | * [[GltB]] | ||
+ | * [[HemN]] | ||
+ | * [[HemZ]] | ||
* [[IlvD]] | * [[IlvD]] | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
* [[IspG]] | * [[IspG]] | ||
* [[IspH]] | * [[IspH]] | ||
− | * [[ | + | * [[KamA]] |
− | * [[ | + | * [[LeuC]] |
− | * [[ | + | * [[LipA]] |
− | * [[ | + | * [[LutB]] |
− | * [[ | + | * [[MmgE]] |
− | * [[ | + | * [[MoaA]] |
+ | * [[MtaB]] | ||
+ | * [[MutY]] | ||
* [[NadA]] | * [[NadA]] | ||
− | |||
− | |||
− | |||
* [[NarG]] | * [[NarG]] | ||
+ | * [[NarH]] | ||
* [[NasC]] | * [[NasC]] | ||
* [[NasD]] | * [[NasD]] | ||
+ | * [[NasE]] | ||
* [[NsrR]] | * [[NsrR]] | ||
+ | * [[Nth]] | ||
+ | * [[PucE]] | ||
+ | * [[PurF]] | ||
+ | * [[PyrK]] | ||
+ | * [[QcrA]] | ||
+ | * [[QueE]] | ||
* [[QueG]] | * [[QueG]] | ||
− | * [[ | + | * [[RlmCD]] |
− | * [[ | + | * [[SdaAA]] |
− | * [[ | + | * [[SdaAB]] |
− | |||
− | |||
* [[SdhB]] | * [[SdhB]] | ||
− | * [[ | + | * [[SkfB]] |
− | * [[ | + | * [[SplB]] |
+ | * [[SufA]] | ||
+ | * [[SufB]] | ||
* [[ThiC]] | * [[ThiC]] | ||
− | * [[ | + | * [[YaaT]] |
− | * [[ | + | * [[YfjO]] |
− | * [[ | + | * [[YloN]] |
* [[YmcB]] | * [[YmcB]] | ||
− | * [[ | + | * [[YsfD]] |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
==[2 Fe-2 S] cluster== | ==[2 Fe-2 S] cluster== | ||
− | * [[ | + | * [[ForC1]] |
+ | * [[ForC2]] | ||
* [[YoaE]] | * [[YoaE]] | ||
* [[YyaE]] | * [[YyaE]] | ||
* [[YydG]] | * [[YydG]] | ||
* [[YhfW]] | * [[YhfW]] | ||
− | |||
* [[YfkA]] | * [[YfkA]] | ||
* [[YtqA]] | * [[YtqA]] | ||
Line 295: | Line 335: | ||
= Thiamine pyrophosphate, TPP = | = Thiamine pyrophosphate, TPP = | ||
− | * [[ | + | * [[AcoA]] |
* [[AlsS]] | * [[AlsS]] | ||
− | + | * [[BkdAA]] | |
− | + | * [[Dxs]] | |
+ | * [[IlvB]] | ||
+ | * [[IolD]] | ||
+ | * [[OdhA]] | ||
* [[PdhA]] | * [[PdhA]] | ||
+ | * [[Tkt]] | ||
+ | * [[YdaP]] | ||
= Lipoic acid = | = Lipoic acid = |
Latest revision as of 09:32, 30 October 2024
Contents
- 1 NAD+
- 2 NADP+
- 3 FAD
- 4 FMN
- 5 Additional Flavoproteins
- 6 S-adenosyl-L-methionine (SAM)
- 7 Menachinone
- 8 Biotin
- 9 Cobalamin
- 10 Calcium
- 11 Copper
- 12 Ammonium
- 13 Nickel
- 14 Magnesium
- 15 Manganese
- 16 Zinc
- 17 MoCo (molybdenum cofactor, molybdopterin)
- 18 Iron-sulfur cluster
- 19 Heme A
- 20 Heme b
- 21 Heme d
- 22 Protoheme IX
- 23 Heme (unspecified )
- 24 Thiamine pyrophosphate, TPP
- 25 Lipoic acid
- 26 Pyridoxyl phosphate, PLP
- 27 Tetrahydrofalate
NAD+
- Ald
- AraM
- BacC
- BdhA
- DhaS
- IolX
- LplD
- IolG
- GapA
- GutB
- RocG
- GudB
- Mdh
- MelA
- NasE
- NtdC
- RhaEW
- Tdh
- TyrA
- YcbD
- YycR
NADP+
FAD
- AcdA
- AcoL
- AhpF
- AlsS
- AroF
- CysJ
- CypB (YrhJ)
- EtfA
- EtfB
- FadE
- FadM
- GidA
- GlpD
- HemY
- Hmp
- IlvB
- LpdV
- MmgC
- MurB
- NadB
- NasB
- NasD
- Nox
- PdhD
- PucC
- PutB
- PyrK
- RibC
- SdhA
- ThiO
- TrmFO
- TrxB
- YdbM
- YcgT
- YdaP
- YetM
- YetO
- YgaK
- YhjG
- YitJ
- YitY
- YjlD
- YngJ
- YoaI
- YobN
- YqiG
- YsfC
- YumB
- YumC
- YurR
- YutJ
- YvdP
FMN
Additional Flavoproteins
Peter Macheroux, Barbara Kappes, Steven E Ealick
Flavogenomics--a genomic and structural view of flavin-dependent proteins.
FEBS J: 2011, 278(15);2625-34
[PubMed:21635694]
[WorldCat.org]
[DOI]
(I p)
S-adenosyl-L-methionine (SAM)
Menachinone
Biotin
Cobalamin
Calcium
Copper
Ammonium
Nickel
Mark A Farrugia, Lee Macomber, Robert P Hausinger
Biosynthesis of the urease metallocenter.
J Biol Chem: 2013, 288(19);13178-85
[PubMed:23539618]
[WorldCat.org]
[DOI]
(I p)
Harini Kaluarachchi, Kim C Chan Chung, Deborah B Zamble
Microbial nickel proteins.
Nat Prod Rep: 2010, 27(5);681-94
[PubMed:20442959]
[WorldCat.org]
[DOI]
(I p)
Stephen W Ragsdale
Nickel-based Enzyme Systems.
J Biol Chem: 2009, 284(28);18571-5
[PubMed:19363030]
[WorldCat.org]
[DOI]
(P p)
Magnesium
Manganese
- AlsS
- CdaA
- ComEC
- CotH
- DisA
- LplD
- LtaS
- MelA
- MutT
- NrdF
- NrnA
- OxdC
- PgpH
- PpaC
- RecJ
- RnhB
- RnhC
- RocB
- RocF
- RsbU
- SpoIIE
- YerA
- YhfI
- YisK
- YloC
- YpgQ
- YvcI
dimanganic-tyrosyl radical cofactor
Zinc
MoCo (molybdenum cofactor, molybdopterin)
Iron-sulfur cluster
- AddB
- AlbA
- BioB
- CitB
- CysI
- Fer
- Fnr
- ForC1
- ForC2
- GltA
- GltB
- HemN
- HemZ
- IlvD
- IspG
- IspH
- KamA
- LeuC
- LipA
- LutB
- MmgE
- MoaA
- MtaB
- MutY
- NadA
- NarG
- NarH
- NasC
- NasD
- NasE
- NsrR
- Nth
- PucE
- PurF
- PyrK
- QcrA
- QueE
- QueG
- RlmCD
- SdaAA
- SdaAB
- SdhB
- SkfB
- SplB
- SufA
- SufB
- ThiC
- YaaT
- YfjO
- YloN
- YmcB
- YsfD
[2 Fe-2 S] cluster
Heme A
Heme b
Heme d
Protoheme IX
Heme (unspecified )
Thiamine pyrophosphate, TPP
Lipoic acid
E2 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase
H protein of the glycine cleavage system
Pyridoxyl phosphate, PLP
- AlaT
- Alr
- ArgD
- AspB
- BacF
- BioA
- BioF
- CysK
- Dat
- DsdA
- EpsN
- GabR
- GabT
- GcvPB
- GlgP
- GlyA
- GsaB
- HemL
- HisC
- IlvA
- KamA
- Kbl
- LysA
- MccA
- MccB
- MetC
- MetI
- MtnE
- NifS
- NifZ
- NtdA
- PabC
- PatA
- PatB
- PucG
- RocD
- SerC
- SpeA
- SpsC
- SufS
- ThrC
- TrpB
- YaaO
- YbgE
- YcbU
- YcxD
- YdeF
- YdeL
- YdfD
- YhdI
- YhdR
- YhxA
- YisV
- YlmE
- YnbB
- YncD
- YodT
- YrvO
- YtkP
- YwaA