epsI

epsI
168

glycosyltransferase, synthesis of extracellular poly-N-acetylglucosamine

Locus
BSU_34290
Molecular weight
41.35 kDa
Isoelectric point
8.04
Protein length
358 aaSequenceBlast
Gene length
1077 bpSequenceBlast
Function
synthesis of extracellular poly-N-acetylglucosamine
Product
glycosyltransferase
Essential
no
Synonyms
epsI, yveS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5039 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,520,030  3,521,106
The EAR RNA switch
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The protein
Protein family
polysaccharide pyruvyl transferase family (with EpsO and YxaB, according to UniProt)
Structure
P71058 (AlphaFold)
Paralogous protein(s)
YxaB
Expression and Regulation
Operons
Genes
epsA-epsB-epsC-epsD-epsE-epsF-epsG-epsH-epsI-epsJ-epsK-epsL-epsM-epsN-epsO
Description
PubMed
Regulation
repressed by SinR PubMed
Regulatory mechanism
RemA: activation, PubMed, in remA regulon
AbrB: repression, PubMed, in abrB regulon
SinR: anti-activation, (prevents binding of RemA) PubMed, in sinR regulon
EAR riboswitch: processive antitermination, in EAR riboswitch
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
induction by sequestration of SinR by SinI or SlrA PubMed
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epsA→epsO

2025-04-02 11:08:39

ghost

150

972f8e32dbf02ccc05ec1b86b52f3e7c715bf4da

DAC70A15EA1F43CB18727990D26DF72F59759165

Biological materials
Mutant
MGNA-B612 (yveS::erm), available at the NBRP B. subtilis, Japan
BKE34290 (epsI::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCCTCACCCTCTGTTT,  downstream forward: _UP4_CAATGATCCCGCTCGTCAGC
BKK34290 (epsI::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCCTCACCCTCTGTTT,  downstream forward: _UP4_CAATGATCCCGCTCGTCAGC
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
References
Reviews
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6EBD8F7065B6C1996067F3120DD9CFEA91D3A444

Page visits: 3589

Time of last update: 2025-04-16 03:33:50

Author of last update: Melvin.boenninger