yloC
168
endoribonuclease
locus
BSU_15660
Molecular weight
33.48 kDa
pI
4.87
function
unknown
product
endoribonuclease YloC
essential
no
synonyms
yloC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1561 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,640,720 1,641,595
The protein
Catalyzed reaction/ biological activity
cleavage of single-stranded RNA, preferentially at U residues [pubmed|34815358]
Protein family
UPF0701 family (single member, according to UniProt)
[wiki|Cofactors]
Mn2+ [pubmed|34815358]
Structure
[PDB|8HVJ] (from E. coli, 30% identity) [pubmed|37535940]
[PDB|8VES] (from E. coli, 30% identity) [pubmed|39180400]
[AF|O34441]
Expression and Regulation
Operons
genes
[gene|A57D2C1536F3E93CD687C28C59FF297355CAB303|yloC]-[gene|6AF1CB8998BE9C71DF4F1201A7F74FF7E75CB799|remA]-[gene|1BC994DE60A7BB35DEDD7154581A396D29AA94A7|gmk]-[gene|921933B6B893083F151AABDEDCBC65F2E55677BE|yloH]
description
[pubmed|22383849]
regulation
expressed during vegetative growth and early during sporulation in the forespore ([protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]) [Pubmed|23396918]
sigma factors
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|23396918], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
genes
[gene|A57D2C1536F3E93CD687C28C59FF297355CAB303|yloC]-[gene|6AF1CB8998BE9C71DF4F1201A7F74FF7E75CB799|remA]-[gene|1BC994DE60A7BB35DEDD7154581A396D29AA94A7|gmk]-[gene|921933B6B893083F151AABDEDCBC65F2E55677BE|yloH]-[gene|2B67C63442F28F6BCBA3BA6DE4B563C73E8DF16C|coaBC]-[gene|AF5ADDA2A98EC18BB72A81AA0336E639C0D1F430|priA]-[gene|3D41FB608DB70B9482312A1BBCCDBDA7FB713AFA|defA]-[gene|06971E9AAB033E2878914A76645F99E97CE8A90A|fmt]-[gene|1370D8783450D538C71E3DE8EA5B37DFEE073FF0|yloM]-[gene|5DEBD84E5937DB8B7F29C729FAA0076DF86A5451|yloN]
description
[pubmed|22383849]
genes
[gene|7821A09DADC6EAF589A882F05CC34BE900E06F2A|yloB]-[gene|A57D2C1536F3E93CD687C28C59FF297355CAB303|yloC]-[gene|6AF1CB8998BE9C71DF4F1201A7F74FF7E75CB799|remA]-[gene|1BC994DE60A7BB35DEDD7154581A396D29AA94A7|gmk]-[gene|921933B6B893083F151AABDEDCBC65F2E55677BE|yloH]
description
[pubmed|22383849]
regulation
expressed during sporulation in the mother cell [pubmed|12161109]
Biological materials
Mutant
GP2609 (Δ[gene|A57D2C1536F3E93CD687C28C59FF297355CAB303|yloC]::''cat''), available in [wiki|Jörg Stülke]'s lab
MGNA-B131 (yloC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1130 NBRP B. subtilis, Japan]
BKE15660 ([gene|A57D2C1536F3E93CD687C28C59FF297355CAB303|yloC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTAAAACACCCAATTC, downstream forward: _UP4_TAGTGACTGTGCGTATTGTT
BKK15660 ([gene|A57D2C1536F3E93CD687C28C59FF297355CAB303|yloC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTAAAACACCCAATTC, downstream forward: _UP4_TAGTGACTGTGCGTATTGTT
References
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Time of last update: 2025-01-04 17:10:19
Author of last update: Jstuelk