Essential genes

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Genes in this functional category

Protein synthesis, secretion and quality control

Aminoacyl-tRNA synthetases

Ribosomal proteins

Ribosome assembly

rRNA modification/maturation

tRNA modification/maturation

Translation factors

Translation/ other

Protein secretion/ chaperones/ protein quality control

Cell envelope and cell division

Cell wall synthesis

Cell division

Cell shape

Metabolism

Central energy metabolism

Biosynthesis of amino acids

Biosynthesis of lipids

Biosynthesis of nucleotides

Biosynthesis of cofactors

Ion homeostasis

Biosynthesis of iron-sulphur clusters

Phosphate metabolism

DNA replication, modification, and chromosome maintenance

DNA replication

Chromosome condensation/ segregation

DNA restriction/modification

RNA synthesis and degradation

Transcription

RNases

Detoxification systems

Unknown

Important original publications

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