gatA

168

production of glutamyl-tRNA(Gln)

Locus: BSU_06680

Molecular weight: 52.50 kDa

Isoelectric point: 5.24

Protein length: 485 aa

Gene length: 1458 bp

Function: translation

Product: glutamyl-tRNA(Gln) amidotransferase subunit A

Essential: yes

E.C.: 6.3.5.7

Synonyms: gatA, yerM, yedB

Genomic Context

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Categories containing this gene/protein

Information processing, Protein synthesis, modification and degradation, Translation, Aminoacyl-tRNA synthetases

Groups of genes, Essential genes

List of homologs in different organisms, belongs to COG0154 (Galperin et al., 2021)

Gene

Coordinates: 729,038 → 730,495

Phenotypes of a mutant

essential PubMed

The protein

Catalyzed reaction/ biological activity

ATP + H₂O + L-glutamine + L-glutamyl-tRNA^Gln --> ADP + H⁺ + L-glutamate + L-glutaminyl-tRNA^Gln + phosphate (according to UniProt)

Protein family

amidase family (single member, according to UniProt)

Structure

2DF4 (PDB) (GatA-GatB-GatC complex from Staphylococcus aureus) PubMed
O06491 (AlphaFold)

Expression and Regulation

Operons

Genes: gatC-gatA-gatB

Description: PubMed

Biological materials

Mutant

MGNA-B446 (yerM::erm), available at the NBRP B. subtilis, Japan

References

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