Essential genes

Parent category	6. Groups of genes
Neighbouring categories	6.1. Essential genes 6.2. Membrane proteins 6.3. GTP-binding proteins 6.4. Phosphoproteins 6.5. Universally conserved proteins 6.6. Poorly characterized/ putative enzymes 6.7. Proteins of unknown function 6.8. Short peptides 6.9. ncRNA 6.10. Pseudogenes
Related categories	none
Overview on the categories (Excel file) All genes and their categories (Excel file)

Genes in this functional category

Aminoacyl-tRNA synthetases

• alaS
• argS
• asnS
• aspS
• cysS
• gatA
• gatB
• gatC
• gltX
• glyS
• hisS
• ileS
• leuS
• lysS
• metS
• pheS
• pheT
• proS
• serS
• trpS
• tyrS
• valS

Ribosomal proteins

• rplB
• rplC
• rplD
• rplE
• rplF
• rplJ
• rplL
• rplM
• rplN
• rplP
• rplQ
• rplR
• rplS
• rplT
• rplU
• rplX
• rpmA
• rpmD
• rpsB
• rpsC
• rpsD
• rpsE
• rpsG
• rpsH
• rpsI
• rpsJ
• rpsK
• rpsL
• rpsM
• rpsN
• rpsO
• rpsP
• rpsQ
• rpsR
• rpsS

Translation/ other

• fusA
• infA
• infB
• infC
• map
• tilS
• tsf
• tufA

DNA replication

• dnaA
• dnaB
• dnaC
• dnaD
• dnaE
• dnaG
• dnaI
• dnaN
• dnaX
• ligA
• pcrA
• polC
• ssbA

Transcription

• nusA
• rpoA
• rpoB
• rpoC
• sigA

RNases

• rnc
• rnjA
• rnpA
• rny
• rnz

Other

• accA
• accB
• accC
• accD
• acpA
• acpS
• adk
• alr
• asd
• birA
• cca
• cdsA
• cmk
• cspR
• dapA
• dapB
• dapF
• ddl
• dfrA
• dgkB
• divIB
• divIC
• dxs
• era
• fabD
• fabF
• fabG
• ffh
• fmt
• folD
• frr
• ftsA
• ftsL
• ftsW
• ftsZ
• gcaD
• gcp
• glmM
• glmS
• glyA
• glyQ
• gmk
• gpsA
• groEL
• groES
• guaB
• gyrA
• gyrB
• hbs
• hepS
• hepT
• hlpB
• holA
• holB
• hprT
• ispC
• ispD
• ispE
• ispF
• ispG
• ispH
• menA
• menB
• menC
• menD
• menE
• menH
• metK

• mnaA
• mraY
• mreB
• mreC
• mreD
• mrpA
• mrpB
• mrpC
• mrpD
• mrpF
• murAA
• murB
• murC
• murD
• murE
• murF
• murG
• nadD
• nadE
• nadF
• nrdE
• nrdF
• nrdI

• obg
• odhB
• parC
• parE
• pbpB

• pdhA
• pgsA

• plsC
• plsX
• plsY
• pncB

• ppaC
• prfA
• prfB
• priA

• prs
• prsA
• pyrG
• racE
• rbgA
• resB
• resC

• rodA

• scpA
• scr
• secA
• secE
• secY

• sknR
• smc
• spoVC

• sufB
• sufC
• sufD
• sufS
• sufU
• tagB
• tagD
• tagF
• tagG
• tagH
• tagO

• tmk
• trmD
• trmU

• trxA
• trxB

• uppS

• walK
• walR
• ycgG
• yddT
• ydiC
• ydiO
• ydiP
• yfkN
• yhdL
• ykuQ
• ykuR
• ylaN
• yomL
• yphC
• ypuF
• yqeH
• yrvO
• ysxC
• ytaG
• yumC

Important original publications

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)

Alison Hunt, Joy P Rawlins, Helena B Thomaides, Jeff Errington
Functional analysis of 11 putative essential genes in Bacillus subtilis.
Microbiology (Reading): 2006, 152(Pt 10);2895-2907
[PubMed:17005971] [WorldCat.org] [DOI] (P p)

K Kobayashi, S D Ehrlich, A Albertini, G Amati, K K Andersen, M Arnaud, K Asai, S Ashikaga, S Aymerich, P Bessieres, F Boland, S C Brignell, S Bron, K Bunai, J Chapuis, L C Christiansen, A Danchin, M Débarbouille, E Dervyn, E Deuerling, K Devine, S K Devine, O Dreesen, J Errington, S Fillinger, S J Foster, Y Fujita, A Galizzi, R Gardan, C Eschevins, T Fukushima, K Haga, C R Harwood, M Hecker, D Hosoya, M F Hullo, H Kakeshita, D Karamata, Y Kasahara, F Kawamura, K Koga, P Koski, R Kuwana, D Imamura, M Ishimaru, S Ishikawa, I Ishio, D Le Coq, A Masson, C Mauël, R Meima, R P Mellado, A Moir, S Moriya, E Nagakawa, H Nanamiya, S Nakai, P Nygaard, M Ogura, T Ohanan, M O'Reilly, M O'Rourke, Z Pragai, H M Pooley, G Rapoport, J P Rawlins, L A Rivas, C Rivolta, A Sadaie, Y Sadaie, M Sarvas, T Sato, H H Saxild, E Scanlan, W Schumann, J F M L Seegers, J Sekiguchi, A Sekowska, S J Séror, M Simon, P Stragier, R Studer, H Takamatsu, T Tanaka, M Takeuchi, H B Thomaides, V Vagner, J M van Dijl, K Watabe, A Wipat, H Yamamoto, M Yamamoto, Y Yamamoto, K Yamane, K Yata, K Yoshida, H Yoshikawa, U Zuber, N Ogasawara
Essential Bacillus subtilis genes.
Proc Natl Acad Sci U S A: 2003, 100(8);4678-83
[PubMed:12682299] [WorldCat.org] [DOI] (P p)