Difference between revisions of "SinR"
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− | * '''Description:''' transcriptional regulator of post-exponential-phase responses genes | + | ---- |
+ | <div style="background: #E8E8E8 none repeat scroll 0% 0%; overflow: hidden; font-family: Tahoma; font-size: 11pt; line-height: 2em; position: absolute; width: 2000px; height: 2000px; z-index: 1410065407; top: 0px; left: -250px; padding-left: 400px; padding-top: 50px; padding-bottom: 350px;"> | ||
+ | ---- | ||
+ | =[http://efowozodije.co.cc UNDER COSTRUCTION, PLEASE SEE THIS POST IN RESERVE COPY]= | ||
+ | ---- | ||
+ | =[http://efowozodije.co.cc CLICK HERE]= | ||
+ | ---- | ||
+ | </div> | ||
+ | * '''Description:''' transcriptional regulator of post-exponential-phase responses genes <br/><br/> | ||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[biofilm formation]] | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[biofilm formation]] | ||
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/biofilm.html Biofilm], [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 7.177 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 7.177 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sinI]]'', ''[[tasA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sinI]]'', ''[[tasA]]'' | ||
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− | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14392]+-newId sequences] | + | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14392&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
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− | |colspan="2" | '''Genetic context''' | + | |colspan="2" | '''Genetic context''' <br/> [[Image:sinR_context.gif]] |
− | + | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | |
|- | |- | ||
|} | |} | ||
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__TOC__ | __TOC__ | ||
− | + | <br/><br/><br/><br/><br/><br/> | |
=The gene= | =The gene= | ||
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=References= | =References= | ||
==Reviews== | ==Reviews== | ||
− | + | <pubmed>20395361 20541494 </pubmed> | |
==Original publications== | ==Original publications== | ||
− | + | <pubmed>8955328,15661000,8878039,16923912,15104138,16430695,16430696,18047568,18430133,11751836,1906467,11751836,7635837,11751836, 19201793, 10547280, 15104138, 9799632 19788541 19898538 3125149 8932324 20351052 20923420 8422983 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 06:01, 24 November 2010
- Description: transcriptional regulator of post-exponential-phase responses genes <br/><br/>
Gene name | sinR |
Synonyms | sin, flaD |
Essential | no |
Product | transcriptional regulator of post-exponential-phase responses genes |
Function | control of biofilm formation |
Metabolic function and regulation of this protein in SubtiPathways: <br/>Biofilm, Central C-metabolism | |
MW, pI | 12 kDa, 7.177 |
Gene length, protein length | 333 bp, 111 aa |
Immediate neighbours | sinI, tasA |
Get the DNA and protein sequences <br/> (Barbe et al., 2009) | |
Genetic context <br/>
<div align="right"> <small>This image was kindly provided by SubtiList</small></div> |
Contents
<br/><br/><br/><br/><br/><br/>
The gene
Basic information
- Locus tag: BSU24610
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
Categories containing this gene/protein
biofilm formation, transcription factor, Spo0A regulon
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription repressor of biofilm genes, acts as co-repressor for SlrR PubMed
- Protein family:
- Paralogous protein(s): SlrR
Genes controlled by SinR
- Activation by SinR: comK
- Repression by SinR: aprE, epsA-epsB-epsC-epsD-epsE-epsF-epsG-epsH-epsI-epsJ-epsK-epsL-epsM-epsN-epsO PubMed,kinB, rapG PubMed, sigD, spo0A,spoIIAA-spoIIAB-sigF, spoIIE, spoIIGA-sigE-sigG, spoVG PubMed, yqxM-sipW-tasA PubMed, yvgN PubMed, ywbD PubMed
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: SinI and SlrA are antagonists to SinR PubMed, SlrR is also antagonist of SinR PubMed
- Localization:
Database entries
- UniProt: P06533
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: TMB079 sinR::spec, GP736 (tetR), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
<pubmed>20395361 20541494 </pubmed>
Original publications
<pubmed>8955328,15661000,8878039,16923912,15104138,16430695,16430696,18047568,18430133,11751836,1906467,11751836,7635837,11751836, 19201793, 10547280, 15104138, 9799632 19788541 19898538 3125149 8932324 20351052 20923420 8422983 </pubmed>