Difference between revisions of "Essential genes"
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== Genes in this functional category == | == Genes in this functional category == | ||
| + | === Metabolism === | ||
| + | ==== Central energy metabolism ==== | ||
| + | * ''[[odhB]]'' | ||
| + | * ''[[pdhA]]'' | ||
| + | * ''[[resB]]'' | ||
| + | * ''[[resC]]'' | ||
| + | * ''[[yumC]]'' | ||
| + | ==== Glycolysis ==== | ||
| + | * ''[[eno]]'' | ||
| + | * ''[[gapA]]'' | ||
| + | * ''[[pgm]]'' | ||
| + | ==== Biosynthesis of amino acids ==== | ||
| + | * ''[[glyA]]'' | ||
| + | * ''[[metK]]'' | ||
| + | |||
| + | ==== Biosynthesis of lipids ==== | ||
| + | * ''[[accA]]'' | ||
| + | * ''[[accB]]'' | ||
| + | * ''[[accC]]'' | ||
| + | * ''[[accD]]'' | ||
| + | * ''[[acpA]]'' | ||
| + | * ''[[acpS]]'' | ||
| + | * ''[[cdsA]]'' | ||
| + | * ''[[fabD]]'' | ||
| + | * ''[[fabF]]'' | ||
| + | * ''[[fabG]]'' | ||
| + | * ''[[gpsA]]'' | ||
| + | * ''[[ispC]]'' | ||
| + | * ''[[ispD]]'' | ||
| + | * ''[[ispE]]'' | ||
| + | * ''[[ispF]]'' | ||
| + | * ''[[ispG]]'' | ||
| + | * ''[[ispH]]'' | ||
| + | * ''[[pgsA]]'' | ||
| + | * ''[[plsC]]'' | ||
| + | * ''[[plsX]]'' | ||
| + | * ''[[plsY]]'' | ||
| + | * ''[[ywpB]]'' | ||
| + | |||
| + | ==== Biosynthesis of nucleotides ==== | ||
| + | * ''[[adk]]'' | ||
| + | * ''[[cmk]]'' | ||
| + | * ''[[gmk]]'' | ||
| + | * ''[[guaB]]'' | ||
| + | * ''[[hprT]]'' | ||
| + | * ''[[nrdE]]'' | ||
| + | * ''[[nrdF]]'' | ||
| + | * ''[[nrdI]]'' | ||
| + | * ''[[prs]]'' | ||
| + | * ''[[pyrG]]'' | ||
| + | * ''[[tmk]]'' | ||
| + | |||
| + | ==== Biosynthesis of cofactors ==== | ||
| + | * ''[[birA]]'' | ||
| + | * ''[[dfrA]]'' | ||
| + | * ''[[dxs]]'' | ||
| + | * ''[[hepS]]'' | ||
| + | * ''[[hepT]]'' | ||
| + | * ''[[menA]]'' | ||
| + | * ''[[menB]]'' | ||
| + | * ''[[menC]]'' | ||
| + | * ''[[menD]]'' | ||
| + | * ''[[menE]]'' | ||
| + | * ''[[menH]]'' | ||
| + | * ''[[nadD]]'' | ||
| + | * ''[[nadE]]'' | ||
| + | * ''[[nadF]]'' | ||
| + | * ''[[ribC]]'' | ||
| + | * ''[[ytaG]]'' | ||
| + | |||
| + | ==== Metal ion transport ==== | ||
| + | * ''[[mntA]]'' | ||
| + | * ''[[mrpA]]'' | ||
| + | * ''[[mrpB]]'' | ||
| + | * ''[[mrpC]]'' | ||
| + | * ''[[mrpD]]'' | ||
| + | * ''[[mrpF]]'' | ||
| + | |||
| + | ==== Biosynthesis of iron-sulphur clusters ==== | ||
| + | * ''[[sufB]]'' | ||
| + | * ''[[sufC]]'' | ||
| + | * ''[[sufD]]'' | ||
| + | * ''[[sufS]]'' | ||
| + | * ''[[sufU]]'' | ||
| + | |||
| + | ==== Phosphate metabolism ==== | ||
| + | * ''[[ppaC]]'' | ||
| + | * ''[[yfkN]]'' | ||
=== Protein synthesis, secretion and quality control === | === Protein synthesis, secretion and quality control === | ||
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* ''[[mreD]]'' | * ''[[mreD]]'' | ||
* ''[[rodA]]'' | * ''[[rodA]]'' | ||
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=== DNA replication and chromosome maintenance === | === DNA replication and chromosome maintenance === | ||
Revision as of 13:03, 12 September 2013
| Parent category | |
| Neighbouring categories |
|
| Related categories |
none |
Contents
- 1 Genes in this functional category
- 2 The list of essential genes according to Kobayashi et al. (2003)
- 3 Important original publications
- 4 Back to categories
Genes in this functional category
Metabolism
Central energy metabolism
Glycolysis
Biosynthesis of amino acids
Biosynthesis of lipids
- accA
- accB
- accC
- accD
- acpA
- acpS
- cdsA
- fabD
- fabF
- fabG
- gpsA
- ispC
- ispD
- ispE
- ispF
- ispG
- ispH
- pgsA
- plsC
- plsX
- plsY
- ywpB
Biosynthesis of nucleotides
Biosynthesis of cofactors
Metal ion transport
Biosynthesis of iron-sulphur clusters
Phosphate metabolism
Protein synthesis, secretion and quality control
Aminoacyl-tRNA synthetases
- alaS
- argS
- asnS
- aspS
- cysS
- gatA
- gatB
- gatC
- gltX
- glyQ
- glyS
- hisS
- ileS
- leuS
- lysS
- metS
- pheS
- pheT
- proS
- serS
- trpS
- tyrS
- valS
Ribosomal proteins
- rplB
- rplC
- rplD
- rplE
- rplF
- rplJ
- rplL
- rplM
- rplN
- rplP
- rplQ
- rplR
- rplS
- rplT
- rplU
- rplX
- rpmA
- rpmD
- rpsB
- rpsC
- rpsD
- rpsE
- rpsG
- rpsH
- rpsI
- rpsJ
- rpsK
- rpsL
- rpsM
- rpsN
- rpsO
- rpsP
- rpsQ
- rpsR
- rpsS
Ribosome assembly
rRNA modification/maturation
tRNA modification/maturation
Translation factors
Translation/ other
Protein secretion/ chaperones/ protein quality control
Cell envelope and cell division
Cell wall synthesis
- alr
- asd
- dapA
- dapB
- dapF
- ddl
- gcaD
- glmM
- glmS
- murAA
- murB
- murC
- murD
- murE
- murF
- murG
- patA
- pbpB
- racE
- tagB
- tagD
- tagF
- tagG
- tagH
- tagO
- uppS
- walK
- walR
- ykuQ
- ykuR
Cell division
Cell shape
DNA replication and chromosome maintenance
DNA replication
Chromosome condensation/ segregation
RNA synthesis and degradation
Transcription
RNases
Protective functions
Unknown
The list of essential genes according to Kobayashi et al. (2003)
Important original publications
Fabian M Commichau, Nico Pietack, Jörg Stülke
Essential genes in Bacillus subtilis: a re-evaluation after ten years.
Mol Biosyst: 2013, 9(6);1068-75
[PubMed:23420519]
[WorldCat.org]
[DOI]
(I p)
Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254]
[WorldCat.org]
[DOI]
(P p)
Alison Hunt, Joy P Rawlins, Helena B Thomaides, Jeff Errington
Functional analysis of 11 putative essential genes in Bacillus subtilis.
Microbiology (Reading): 2006, 152(Pt 10);2895-2907
[PubMed:17005971]
[WorldCat.org]
[DOI]
(P p)
K Kobayashi, S D Ehrlich, A Albertini, G Amati, K K Andersen, M Arnaud, K Asai, S Ashikaga, S Aymerich, P Bessieres, F Boland, S C Brignell, S Bron, K Bunai, J Chapuis, L C Christiansen, A Danchin, M Débarbouille, E Dervyn, E Deuerling, K Devine, S K Devine, O Dreesen, J Errington, S Fillinger, S J Foster, Y Fujita, A Galizzi, R Gardan, C Eschevins, T Fukushima, K Haga, C R Harwood, M Hecker, D Hosoya, M F Hullo, H Kakeshita, D Karamata, Y Kasahara, F Kawamura, K Koga, P Koski, R Kuwana, D Imamura, M Ishimaru, S Ishikawa, I Ishio, D Le Coq, A Masson, C Mauël, R Meima, R P Mellado, A Moir, S Moriya, E Nagakawa, H Nanamiya, S Nakai, P Nygaard, M Ogura, T Ohanan, M O'Reilly, M O'Rourke, Z Pragai, H M Pooley, G Rapoport, J P Rawlins, L A Rivas, C Rivolta, A Sadaie, Y Sadaie, M Sarvas, T Sato, H H Saxild, E Scanlan, W Schumann, J F M L Seegers, J Sekiguchi, A Sekowska, S J Séror, M Simon, P Stragier, R Studer, H Takamatsu, T Tanaka, M Takeuchi, H B Thomaides, V Vagner, J M van Dijl, K Watabe, A Wipat, H Yamamoto, M Yamamoto, Y Yamamoto, K Yamane, K Yata, K Yoshida, H Yoshikawa, U Zuber, N Ogasawara
Essential Bacillus subtilis genes.
Proc Natl Acad Sci U S A: 2003, 100(8);4678-83
[PubMed:12682299]
[WorldCat.org]
[DOI]
(P p)
