artR
168
high affinity arginine [wiki|ABC transporter ](ATP-binding protein)
locus
BSU_23960
Molecular weight
26.80 kDa
pI
9.13
function
arginine uptake
product
high affinity arginine [wiki|ABC transporter ](ATP-binding protein)
essential
no
synonyms
artR, artM, yqiZ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1126 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,490,574 2,491,296
The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transporter domain] (aa 2-236) (according to UniProt)
Structure
[PDB|4YMS] (from Caldanaerobacter subterraneus, 44% identity) [pubmed|25848002]
[AF|P54537]
Paralogous protein(s)
[protein|B24763A732111026D21C828FF9BE73FB22A123CF|tcyN], [protein|B453986691E1231A1C565D469A2A60EBFF2F6BD3|tcyC], [protein|F8C800CF71D21A1F3265977C4F0EE191D0FFE36A|yxeO], [protein|0D5BC94E21D51373A50D61CE3D0895B3DB28F6B3|pstBB], [protein|0F8048267EC038D8CF673317D969BA27735473A7|yvrO], [protein|468BEA9EAEA589D683DB79B2C689A5C6A22AB67F|glnQ], [protein|434BCED6953BE07D592AC229264C5AD0D04CBAF6|pstBA]
[wiki|Localization]
cell membrane (via [protein|62BD291B91DB0358754957D84A1F3636C247A697|artQ])
Expression and Regulation
Operons
genes
[gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]-[gene|62BD291B91DB0358754957D84A1F3636C247A697|artQ]-[gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]
description
[Pubmed|12107147]
regulation
repressed by casamino acids [Pubmed|12107147]
induced in the absence of [protein|F4097349A563503468A2A14F062AEAC532C7917A|rnpM] [pubmed|30355672]
regulatory mechanism
[protein|F4097349A563503468A2A14F062AEAC532C7917A|rnpM]: unknown, [pubmed|30355672], in [regulon|protein:F4097349A563503468A2A14F062AEAC532C7917A|rnpM regulon]
Biological materials
Mutant
GP1689 Δ([gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]-[gene|62BD291B91DB0358754957D84A1F3636C247A697|artQ]-[gene|6882EF93EC82872B25C88104F62D6603D2514890|artR])::''mls'', available in [wiki|Jörg Stülke]'s lab
GP4156 (Δ[gene|9BFB16C12B31ABD70BBB921BCB9E4201E3BDC92D|rocC]::''aphA3'', Δ[gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]-[gene|62BD291B91DB0358754957D84A1F3636C247A697|artQ]-[gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]::''ermC'', Δ[gene|B46A8BCEC56E6252712E30F8BF8DA6B836FDE2F6|rocE]::''tet'',), available in [wiki|Jörg Stülke]'s lab
MGNA-C383 ([gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2381 NBRP B. subtilis, Japan]
BKE23960 ([gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAATGATTTTGACAGCTTTT, downstream forward: _UP4_TAGAATATAAAAAAGAAGAA
BKK23960 ([gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAATGATTTTGACAGCTTTT, downstream forward: _UP4_TAGAATATAAAAAAGAAGAA
References
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Time of last update: 2024-10-10 18:03:07
Author of last update: Jstuelk