artP
168
high affinity [metabolite|arginine] [wiki|ABC transporter] (binding protein)
locus
BSU_23980
Molecular weight
28.16 kDa
pI
5.09
function
arginine uptake
product
high affinity [metabolite|arginine] [wiki|ABC transporter] (binding protein)
essential
no
synonyms
artP, yqiX
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0834 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,492,029 2,492,796
The protein
Catalyzed reaction/ biological activity
binding of extracellular [metabolite|arginine]
Protein family
[wiki|bacterial solute-binding protein 3 family] (according to UniProt)
Structure
[PDB|4YMX] (from Caldanaerobacter subterraneus, 43% identity) [pubmed|25848002]
[AF|P54535]
[wiki|Localization]
attached to the membrane via [protein|62BD291B91DB0358754957D84A1F3636C247A697|artQ] [Pubmed|10092453]
extracellular (signal peptide) [Pubmed|18957862], membrane [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]-[gene|62BD291B91DB0358754957D84A1F3636C247A697|artQ]-[gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]
description
[Pubmed|12107147]
regulation
repressed by casamino acids [Pubmed|12107147]
induced in the absence of [protein|F4097349A563503468A2A14F062AEAC532C7917A|rnpM] [pubmed|30355672]
regulatory mechanism
[protein|F4097349A563503468A2A14F062AEAC532C7917A|rnpM]: unknown, [pubmed|30355672], in [regulon|protein:F4097349A563503468A2A14F062AEAC532C7917A|rnpM regulon]
Biological materials
Mutant
GP1689 Δ([gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]-[gene|62BD291B91DB0358754957D84A1F3636C247A697|artQ]-[gene|6882EF93EC82872B25C88104F62D6603D2514890|artR])::''mls'', available in [wiki|Jörg Stülke]'s lab
GP4156 (Δ[gene|9BFB16C12B31ABD70BBB921BCB9E4201E3BDC92D|rocC]::''aphA3'', Δ[gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]-[gene|62BD291B91DB0358754957D84A1F3636C247A697|artQ]-[gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]::''ermC'', Δ[gene|B46A8BCEC56E6252712E30F8BF8DA6B836FDE2F6|rocE]::''tet'',), available in [wiki|Jörg Stülke]'s lab
MGNA-C381 ([gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2379 NBRP B. subtilis, Japan]
BKE23980 ([gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23980 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCCATTTCCCCCGTA, downstream forward: _UP4_TAAAAAAAAGCGGCTCAACT
BKK23980 ([gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23980 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCCATTTCCCCCGTA, downstream forward: _UP4_TAAAAAAAAGCGGCTCAACT
References
Page visits: 5412
Time of last update: 2024-12-28 16:05:52
Author of last update: Jstuelk