DNA repair/ recombination

Parent categories	3. Information processing 3.1. Genetics
Neighbouring categories	3.1.1. DNA replication 3.1.2. DNA condensation/ segregation 3.1.3. DNA restriction/ modification 3.1.4. DNA repair/ recombination 3.1.5. Genetic competence 3.1.6. Genetics/ other
Related categories	genetic competence LexA regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

Genes in this functional category

A/P endonucleases

• exoA
• nfo
• nth

Spore-encoded non-homologous end joining system

• ligD
• ykoV

Double strand breaks repair

• recU
• ruvA
• ruvB

Oxidized guanine (GO) DNA repair system

• mutM
• mutTA
• mutY

Excision of prophages

• spoIVCA
• sprA
• sprB

Other proteins

• adaA
• adaB
• addA
• addB
• alkA
• dinB
• dinG
• dprA

• fin
• helD
• hlpB
• lexA

• lrpC
• mfd
• mutL

• mutS
• mutSB
• mutT

• ogt
• pcrA
• pnpA
• polA
• polX
• polY1
• polY2
• radA
• radC
• recA
• recF
• recG
• recJ
• recN
• recO
• recQ
• recR

• recX

• sbcC
• sbcD
• sbcE
• splA
• splB

• ssbA
• ssbB
• ung
• uvrA
• uvrB
• uvrC
• uvrX

• ywjD
• ywqL

Additional candidates (based on similarity)

• aag
• yefB
• yefC
• yfjP
• yhaZ
• yjcD
• yjhB
• yneB
• yobH
• yocI

• yorK
• yozK
• yprA
• ypvA

• yvcI

Key reviews

Juan C Alonso, Paula P Cardenas, Humberto Sanchez, James Hejna, Yuki Suzuki, Kunio Takeyasu
Early steps of double-strand break repair in Bacillus subtilis.
DNA Repair (Amst): 2013, 12(3);162-76
[PubMed:23380520] [WorldCat.org] [DOI] (I p)

Dale B Wigley
Bacterial DNA repair: recent insights into the mechanism of RecBCD, AddAB and AdnAB.
Nat Rev Microbiol: 2013, 11(1);9-13
[PubMed:23202527] [WorldCat.org] [DOI] (I p)

Dawit Kidane, Silvia Ayora, Joann B Sweasy, Peter L Graumann, Juan C Alonso
The cell pole: the site of cross talk between the DNA uptake and genetic recombination machinery.
Crit Rev Biochem Mol Biol: 2012, 47(6);531-55
[PubMed:23046409] [WorldCat.org] [DOI] (I p)

Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559] [WorldCat.org] [DOI] (I p)

Ann Ganesan, Graciela Spivak, Philip C Hanawalt
Transcription-coupled DNA repair in prokaryotes.
Prog Mol Biol Transl Sci: 2012, 110;25-40
[PubMed:22749141] [WorldCat.org] [DOI] (I p)

Silvia Ayora, Begoña Carrasco, Paula P Cárdenas, Carolina E César, Cristina Cañas, Tribhuwan Yadav, Chiara Marchisone, Juan C Alonso
Double-strand break repair in bacteria: a view from Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(6);1055-81
[PubMed:21517913] [WorldCat.org] [DOI] (I p)

Eduardo P C Rocha, Emmanuel Cornet, Bénédicte Michel
Comparative and evolutionary analysis of the bacterial homologous recombination systems.
PLoS Genet: 2005, 1(2);e15
[PubMed:16132081] [WorldCat.org] [DOI] (P p)

Shelley L Lusetti, Michael M Cox
The bacterial RecA protein and the recombinational DNA repair of stalled replication forks.
Annu Rev Biochem: 2002, 71;71-100
[PubMed:12045091] [WorldCat.org] [DOI] (P p)

S Fernández, S Ayora, J C Alonso
Bacillus subtilis homologous recombination: genes and products.
Res Microbiol: 2000, 151(6);481-6
[PubMed:10961463] [WorldCat.org] [DOI] (P p)

Key original publications

Wojciech W Krajewski, Xin Fu, Martin Wilkinson, Nora B Cronin, Mark S Dillingham, Dale B Wigley
Structural basis for translocation by AddAB helicase-nuclease and its arrest at χ sites.
Nature: 2014, 508(7496);416-9
[PubMed:24670664] [WorldCat.org] [DOI] (I p)