trpA
168
tryptophan synthase (alpha subunit)
Locus
BSU_22630
Molecular weight
29.30 kDa
Isoelectric point
4.82
Function
biosynthesis of tryptophan
Product
tryptophan synthase (alpha subunit)
Essential
no
E.C.
4.2.1.20
Synonyms
trpA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0159 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,371,508 2,372,311
The protein
Catalyzed reaction/ biological activity
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine --> D-glyceraldehyde 3-phosphate + H2O + L-tryptophan (according to UniProt)
Protein family
TrpA family (single member, according to UniProt)
Structure
1WQ5 (PDB) (from Escherichia coli, 35% identity, 53% similarity) PubMed
Expression and Regulation
Operons
Biological materials
Mutant
References
Reviews
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Original Publications
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Time of last update: 2025-04-27 17:07:14
Author of last update: Jstuelk