Difference between revisions of "Biofilm formation"
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Revision as of 09:25, 25 June 2012
Biofilms are the result of the multicellular lifestyle of B. subtilis. They are characterized by the formation of a matrix polysaccharide and an amyloid-like protein, TasA. Correction of sfp, epsC, swrAA, and degQ as well as introduction of rapP from a plasmid present in NCIB3610 results in biofilm formation in B. subtilis 168 PubMed.
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Contents
Biofilm formation in SubtiPathways
Labs working on biofilm formation
- Daniel Kearns
- Roberto Kolter
- Oscar Kuipers
- Beth Lazazzera
- Richard Losick
- Nicola Stanley-Wall
- Jörg Stülke
Key genes and operons involved in biofilm formation
- matrix polysaccharide synthesis:
- amyloid protein synthesis, secretion and assembly
- repellent surface layer
- regulation
- KinD
- Spo0A
- biofilm disassembly (D-amino acids produced by RacX and YlmE and norspermidine produced by GabT and YaaO act together in preventing biofilm formation and triggering biofilm disassembly PubMed)
- other proteins required for biofilm formation
Important original publications
Key reviews
Additional reviews: PubMed
