Difference between revisions of "Carbon core metabolism"
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* 2.2.2. [[Utilization of specific carbon sources]] | * 2.2.2. [[Utilization of specific carbon sources]] | ||
|Related= | |Related= | ||
| − | + | * [[regulators of core metabolism]] | |
| + | * [[CcpA regulon]] | ||
| + | * [[CcpC regulon]] | ||
| + | * [[CggR regulon]] | ||
|}} | |}} | ||
| − | == Genes in this functional category == | + | ==Genes in this functional category== |
=== Glycolysis === | === Glycolysis === | ||
| − | * [[cggR]] | + | * ''[[cggR]]'' |
| − | * [[eno]] | + | * ''[[eno]]'' |
| − | * [[fbaA]] | + | * ''[[fbaA]]'' |
| − | * [[gapA]] | + | * ''[[gapA]]'' |
| − | * [[glcT]] | + | * ''[[glcT]]'' |
| − | * [[mgsA]] | + | * ''[[mgsA]]'' |
| − | * [[pfkA]] | + | * ''[[pfkA]]'' |
| − | * [[pgi]] | + | * ''[[pgi]]'' |
| − | * [[pgk]] | + | * ''[[pgk]]'' |
| − | * [[pgm]] | + | * ''[[pgm]]'' |
| − | * [[ptsG]] | + | * ''[[ptsG]]'' |
| − | * [[pyk]] | + | * ''[[pyk]]'' |
| − | * [[tpi]] | + | * ''[[tpi]]'' |
| + | |||
| + | '''see the structures of glycolytic enzymes [http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb50_1.html Glycolytic enzymes: molecules of the month]''' | ||
=== Gluconeogenesis === | === Gluconeogenesis === | ||
| − | * [[ccpN]] | + | * ''[[ccpN]]'' |
| − | * [[eno]] | + | * ''[[eno]]'' |
| − | * [[fbaA]] | + | * ''[[fbaA]]'' |
| − | * [[fbp]] | + | * ''[[fbp]]'' |
| − | * [[gapB]] | + | * ''[[gapB]]'' |
| − | * [[glpX]] | + | * ''[[glpX]]'' |
| − | * [[pckA]] | + | * ''[[pckA]]'' |
| − | * [[pgi]] | + | * ''[[pgi]]'' |
| − | * [[pgk]] | + | * ''[[pgk]]'' |
| − | * [[pgm]] | + | * ''[[pgm]]'' |
| − | * [[tpi]] | + | * ''[[tpi]]'' |
| − | * [[yqfL]] | + | * ''[[yqfL]]'' |
| − | * [[yvcK]] | + | * ''[[yvcK]]'' |
=== Pentose phosphate pathway === | === Pentose phosphate pathway === | ||
| − | * [[gndA]] | + | * ''[[gndA]]'' |
| − | * [[rpe]] | + | * ''[[rpe]]'' |
| − | * [[tkt]] | + | * ''[[tkt]]'' |
| − | * [[ywjH]] | + | * ''[[ykgB]]'' |
| − | * [[ywlF]] | + | * ''[[ywjH]]'' |
| − | * [[zwf]] | + | * ''[[ywlF]]'' |
| + | * ''[[zwf]]'' | ||
=== TCA cycle === | === TCA cycle === | ||
| − | * [[ccpC]] | + | * ''[[ccpC]]'' |
| − | * [[citB]] | + | * ''[[citB]]'' |
| − | * [[citG]] | + | * ''[[citG]]'' |
| − | * [[citZ]] | + | * ''[[citZ]]'' |
| − | * [[fsrA]] | + | * ''[[fsrA]]'' |
| − | * [[icd]] | + | * ''[[icd]]'' |
| − | * [[mdh]] | + | * ''[[mdh]]'' |
| − | * [[odhA]] | + | * ''[[odhA]]'' |
| − | * [[odhB]] | + | * ''[[odhB]]'' |
| − | * [[pdhA]] | + | * ''[[pdhA]]'' |
| − | * [[pdhB]] | + | * ''[[pdhB]]'' |
| − | * [[pdhC]] | + | * ''[[pdhC]]'' |
| − | * [[pdhD]] | + | * ''[[pdhD]]'' |
| − | * [[pycA]] | + | * ''[[pycA]]'' |
| − | * [[sdhA]] | + | * ''[[sdhA]]'' |
| − | * [[sdhB]] | + | * ''[[sdhB]]'' |
| − | * [[sdhC]] | + | * ''[[sdhC]]'' |
| − | * [[sucC]] | + | *'' [[sucC]]'' |
| − | * [[sucD]] | + | * ''[[sucD]]'' |
=== Overflow metabolism === | === Overflow metabolism === | ||
| − | * [[ackA]] | + | * ''[[ackA]]'' |
| − | * [[alsD]] | + | * ''[[alsD]]'' |
| − | * [[alsR]] | + | * ''[[alsR]]'' |
| − | * [[alsS]] | + | * ''[[alsS]]'' |
| − | * [[bdhA]] | + | * ''[[bdhA]]'' |
| − | * [[lctP]] | + | * ''[[lctP]]'' |
| − | * [[ldh]] | + | * ''[[ldh]]'' |
| − | * [[pta]] | + | * ''[[pta]]'' |
| − | * [[rex]] | + | * ''[[rex]]'' |
| + | |||
| + | == Carbon core metabolism in [http://subtiwiki.uni-goettingen.de/subtipathways.html ''Subti''Pathways]: [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central carbon metabolism]== | ||
| + | |||
| + | ==Important original publications== | ||
| + | <pubmed>20933603 19193632 12850135 11489127 19917605 18586936 9131624 18302748 24727859 </pubmed> | ||
| + | |||
| + | ==Reviews== | ||
| + | <pubmed> 11018147 19202299 17982469 16102602 22545791</pubmed> | ||
| + | |||
| + | =Back to [[categories]]= | ||
Latest revision as of 07:06, 15 April 2014
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| Neighbouring categories |
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| Related categories | |
Contents
Genes in this functional category
Glycolysis
see the structures of glycolytic enzymes Glycolytic enzymes: molecules of the month
Gluconeogenesis
Pentose phosphate pathway
TCA cycle
Overflow metabolism
Carbon core metabolism in SubtiPathways: Central carbon metabolism
Important original publications
Hanna Meyer, Hendrikje Weidmann, Ulrike Mäder, Michael Hecker, Uwe Völker, Michael Lalk
A time resolved metabolomics study: the influence of different carbon sources during growth and starvation of Bacillus subtilis.
Mol Biosyst: 2014, 10(7);1812-23
[PubMed:24727859]
[WorldCat.org]
[DOI]
(I p)
Frederik M Meyer, Jan Gerwig, Elke Hammer, Christina Herzberg, Fabian M Commichau, Uwe Völker, Jörg Stülke
Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon.
Metab Eng: 2011, 13(1);18-27
[PubMed:20933603]
[WorldCat.org]
[DOI]
(I p)
Roelco J Kleijn, Joerg M Buescher, Ludovic Le Chat, Matthieu Jules, Stephane Aymerich, Uwe Sauer
Metabolic fluxes during strong carbon catabolite repression by malate in Bacillus subtilis.
J Biol Chem: 2010, 285(3);1587-96
[PubMed:19917605]
[WorldCat.org]
[DOI]
(I p)
Fabian M Commichau, Fabian M Rothe, Christina Herzberg, Eva Wagner, Daniel Hellwig, Martin Lehnik-Habrink, Elke Hammer, Uwe Völker, Jörg Stülke
Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing.
Mol Cell Proteomics: 2009, 8(6);1350-60
[PubMed:19193632]
[WorldCat.org]
[DOI]
(I p)
Simon Tännler, Eliane Fischer, Dominique Le Coq, Thierry Doan, Emmanuel Jamet, Uwe Sauer, Stéphane Aymerich
CcpN controls central carbon fluxes in Bacillus subtilis.
J Bacteriol: 2008, 190(18);6178-87
[PubMed:18586936]
[WorldCat.org]
[DOI]
(I p)
Anne Goelzer, Fadia Bekkal Brikci, Isabelle Martin-Verstraete, Philippe Noirot, Philippe Bessières, Stéphane Aymerich, Vincent Fromion
Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis.
BMC Syst Biol: 2008, 2;20
[PubMed:18302748]
[WorldCat.org]
[DOI]
(I e)
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
H Ludwig, G Homuth, M Schmalisch, F M Dyka, M Hecker, J Stülke
Transcription of glycolytic genes and operons in Bacillus subtilis: evidence for the presence of multiple levels of control of the gapA operon.
Mol Microbiol: 2001, 41(2);409-22
[PubMed:11489127]
[WorldCat.org]
[DOI]
(P p)
U Sauer, V Hatzimanikatis, J E Bailey, M Hochuli, T Szyperski, K Wüthrich
Metabolic fluxes in riboflavin-producing Bacillus subtilis.
Nat Biotechnol: 1997, 15(5);448-52
[PubMed:9131624]
[WorldCat.org]
[DOI]
(P p)
Reviews
Maria Papagianni
Recent advances in engineering the central carbon metabolism of industrially important bacteria.
Microb Cell Fact: 2012, 11;50
[PubMed:22545791]
[WorldCat.org]
[DOI]
(I e)
Yasutaro Fujita
Carbon catabolite control of the metabolic network in Bacillus subtilis.
Biosci Biotechnol Biochem: 2009, 73(2);245-59
[PubMed:19202299]
[WorldCat.org]
[DOI]
(I p)
Abraham L Sonenshein
Control of key metabolic intersections in Bacillus subtilis.
Nat Rev Microbiol: 2007, 5(12);917-27
[PubMed:17982469]
[WorldCat.org]
[DOI]
(I p)
Uwe Sauer, Bernhard J Eikmanns
The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria.
FEMS Microbiol Rev: 2005, 29(4);765-94
[PubMed:16102602]
[WorldCat.org]
[DOI]
(P p)
J Stülke, W Hillen
Regulation of carbon catabolism in Bacillus species.
Annu Rev Microbiol: 2000, 54;849-80
[PubMed:11018147]
[WorldCat.org]
[DOI]
(P p)
