Difference between revisions of "Iron metabolism"
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== Genes in this functional category == | == Genes in this functional category == | ||
| + | * Note: the main systems for iron uptake in ''B. subtilis'' 168 are [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]] and [[EfeO]]-[[EfeU]] with [[EfeB]] {{PubMed|22194458}} | ||
| − | ==[[ABC transporters]] for the[[Iron metabolism|uptake of iron/ siderophores]]== | + | ===[[ABC transporters]] for the[[Iron metabolism|uptake of iron/ siderophores]]=== |
* [[YusV]]-[[FeuB]]-[[FeuC]]-[[FeuA]]: uptake of the siderophores enterobactin and bacillibactin | * [[YusV]]-[[FeuB]]-[[FeuC]]-[[FeuA]]: uptake of the siderophores enterobactin and bacillibactin | ||
* [[FhuC]]-[[FhuB]]-[[FhuG]]-[[FhuD]]-[[YxeB]]: uptake of ferrichrome und ferrioxamine | * [[FhuC]]-[[FhuB]]-[[FhuG]]-[[FhuD]]-[[YxeB]]: uptake of ferrichrome und ferrioxamine | ||
| Line 24: | Line 25: | ||
* [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]]: uptake of iron/citrate | * [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]]: uptake of iron/citrate | ||
| − | == Elemental iron transport system == | + | === Elemental iron transport system === |
* [[EfeO]]-[[EfeU]], [[EfeB]] | * [[EfeO]]-[[EfeU]], [[EfeB]] | ||
| − | == Acquisition of iron/other == | + | === Acquisition of iron/other === |
* [[besA]] | * [[besA]] | ||
* [[btr]] | * [[btr]] | ||
| Line 40: | Line 41: | ||
* [[fbpB]] | * [[fbpB]] | ||
* [[fbpC]] | * [[fbpC]] | ||
| − | + | * [[fsrA]] | |
* [[fur]] | * [[fur]] | ||
* [[mrgA]] | * [[mrgA]] | ||
* [[ybbA]] | * [[ybbA]] | ||
| − | |||
* [[yhfQ]] | * [[yhfQ]] | ||
* [[ymfD]] | * [[ymfD]] | ||
| + | * [[yvmB]] | ||
* [[yvmC]] | * [[yvmC]] | ||
| Line 54: | Line 55: | ||
* [[yvrB]] | * [[yvrB]] | ||
* [[yvrC]] | * [[yvrC]] | ||
| + | |||
| + | === Export of Fe(II)=== | ||
| + | * [[pfeT]] | ||
=== Biosynthesis of iron-sulfur clusters === | === Biosynthesis of iron-sulfur clusters === | ||
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* ''[[sufS]]'' | * ''[[sufS]]'' | ||
* ''[[sufU]]'' | * ''[[sufU]]'' | ||
| + | * ''[[yitW]]'' | ||
==Key reviews== | ==Key reviews== | ||
| − | <pubmed> 20467446 16211402 12732309 23192658 </pubmed> | + | <pubmed> 20467446 16211402 12732309 23192658 25160631 26259870 26488283</pubmed> |
| + | |||
| + | ==Important original publications == | ||
| + | <pubmed>27795321</pubmed> | ||
| + | |||
=Back to [[categories]]= | =Back to [[categories]]= | ||
Latest revision as of 10:21, 1 November 2016
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Contents
Genes in this functional category
- Note: the main systems for iron uptake in B. subtilis 168 are YfmF-YfmD-YfmE-YfmC-YhfQ and EfeO-EfeU with EfeB PubMed
ABC transporters for theuptake of iron/ siderophores
- YusV-FeuB-FeuC-FeuA: uptake of the siderophores enterobactin and bacillibactin
- FhuC-FhuB-FhuG-FhuD-YxeB: uptake of ferrichrome und ferrioxamine
- YclN-YclO-YclP-YclQ: uptake of petrobactin (a siderophore produced by B. anthracis and B. cereus)
- YusV-YfiZ-YfhA-YfiY: uptake of the siderophores schizokinen and arthrobactin
- YfmF-YfmD-YfmE-YfmC-YhfQ: uptake of iron/citrate
Elemental iron transport system
Acquisition of iron/other
Acquisition of iron/ based on similarity
Export of Fe(II)
Biosynthesis of iron-sulfur clusters
Key reviews
Erin L Mettert, Patricia J Kiley
How Is Fe-S Cluster Formation Regulated?
Annu Rev Microbiol: 2015, 69;505-26
[PubMed:26488283]
[WorldCat.org]
[DOI]
(I p)
Zuelay Rosario-Cruz, Jeffrey M Boyd
Physiological roles of bacillithiol in intracellular metal processing.
Curr Genet: 2016, 62(1);59-65
[PubMed:26259870]
[WorldCat.org]
[DOI]
(I p)
John D Helmann
Specificity of metal sensing: iron and manganese homeostasis in Bacillus subtilis.
J Biol Chem: 2014, 289(41);28112-20
[PubMed:25160631]
[WorldCat.org]
[DOI]
(I p)
Marcus Miethke
Molecular strategies of microbial iron assimilation: from high-affinity complexes to cofactor assembly systems.
Metallomics: 2013, 5(1);15-28
[PubMed:23192658]
[WorldCat.org]
[DOI]
(I p)
Béatrice Py, Frédéric Barras
Building Fe-S proteins: bacterial strategies.
Nat Rev Microbiol: 2010, 8(6);436-46
[PubMed:20467446]
[WorldCat.org]
[DOI]
(I p)
M Fontecave, S Ollagnier de Choudens, B Py, F Barras
Mechanisms of iron-sulfur cluster assembly: the SUF machinery.
J Biol Inorg Chem: 2005, 10(7);713-21
[PubMed:16211402]
[WorldCat.org]
[DOI]
(P p)
Patricia J Kiley, Helmut Beinert
The role of Fe-S proteins in sensing and regulation in bacteria.
Curr Opin Microbiol: 2003, 6(2);181-5
[PubMed:12732309]
[WorldCat.org]
[DOI]
(P p)
Important original publications
Emily M Roy, Kevin L Griffith
Characterization of a Novel Iron Acquisition Activity That Coordinates the Iron Response with Population Density under Iron-Replete Conditions in Bacillus subtilis.
J Bacteriol: 2017, 199(1);
[PubMed:27795321]
[WorldCat.org]
[DOI]
(I e)
