meeF

meeF
168

general stress protein, manganese resistance protein

locus
BSU_02920
Molecular weight
29.02 kDa
pI
7.45
Protein length
Gene length
function
resistance to Mn2+ intoxication, co-translocational metalation of Mn2+-dependent membrane and extracellular enzymes
product
manganese resistance protein
essential
no
synonyms
yceF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0861 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
314,025 → 314,798
Phenotypes of a mutant
the [gene|F16A11027D8D320D3D64E44038E29921A946955B|meeF] [gene|F39BC9CA68DD8E80D3ED021272A6F54EA9C57C7B|meeY] double mutant is defective in [category|SW.3.3.5|Protein secretion] [pubmed|37794032]
The protein
Catalyzed reaction/ biological activity
co-translocational metalation of Mn2+-dependent membrane and extracellular enzymes [pubmed|37794032]
Protein family
[wiki|TerC family] [pubmed|37794032]
Structure
[AF|O34447]
Paralogous protein(s)
[protein|F39BC9CA68DD8E80D3ED021272A6F54EA9C57C7B|meeY]
[wiki|Localization]
cell membrane [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|7E4742F30B4C43FBF9DAE0B02948022AE7912A33|yceC]-[gene|DF30A8B195B8D830E131B23C768F07BE61F51150|yceD]-[gene|863E26D497D29B820912A0C0F4A3AE4C6865EC2E|yceE]-[gene|F16A11027D8D320D3D64E44038E29921A946955B|meeF]-[gene|F588108F12C5CA855A24159F28223EF67145D28F|yceG]-[gene|3A9EB32D5627FAB3F7646B7918E54C8D1ADD25DF|yceH]
description
[Pubmed|11866510]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|11544224]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [Pubmed|18179421], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]: sigma factor, [Pubmed|11866510], in [regulon|protein:3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224,15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX]: sigma factor, [Pubmed|19047346], in [regulon|protein:E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX regulon]
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[gene|7E4742F30B4C43FBF9DAE0B02948022AE7912A33|yceC]→[gene|3A9EB32D5627FAB3F7646B7918E54C8D1ADD25DF|yceH]

2024-10-07 17:27:40

ghost

117

1557da8d91643a69a9cc817172bc649767baab90

35ADA58FA11FB35C1D0420A579F4F2F0CD877167

Biological materials
Mutant
MGNA-B986 (yceF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1985 NBRP B. subtilis, Japan]
BKE02920 (Δ[gene|F16A11027D8D320D3D64E44038E29921A946955B|meeF]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGTTTTTTCCTCCTATAA,  downstream forward: _UP4_TAAAACAAAACAAGGAGGGA
BKK02920 (Δ[gene|F16A11027D8D320D3D64E44038E29921A946955B|meeF]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGTTTTTTCCTCCTATAA,  downstream forward: _UP4_TAAAACAAAACAAGGAGGGA
References
Reviews
34037759
Original Publications
15805528,18763711,11866510,10203839,18179421,31685536,37794032

F16A11027D8D320D3D64E44038E29921A946955B

Page visits: 4508

Time of last update: 2024-10-08 02:08:51

Author of last update: Jstuelk