cotW

cotW
168

spore crust protein (insoluble fraction), formation of the spore crust

Locus
BSU_11770
Molecular weight
12.20 kDa
Isoelectric point
9.95
Protein length
105 aaSequenceBlast
Gene length
318 bpSequenceBlast
Function
resistance of the spore
Product
spore crust protein (insoluble fraction)
Essential
no
Synonyms
cotW
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5887 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,251,273  1,251,590
The protein
Structure
Q08310 (AlphaFold)
Localization
spore crust, localization depends on CotX, CotY, and CotZ  PubMed
Expression and Regulation
Operons
Genes
cotV-cotW-cotX
Description
PubMed
Regulation
expressed during sporulation in the mother cell (SigE, SigK, GerE, SpoIIID) PubMed
Regulatory mechanism
GerE: activation, PubMed, in gerE regulon
SpoIIID: activation, PubMed, in spoIIID regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
SigE: sigma factor, PubMed, in sigE regulon
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cotV→cotX

2025-04-04 15:34:08

ghost

68

d2c258d06ac9b622812dc5167b67f8b6cda6f5a0

A452B6601F16F2096F9BDD8987ADC1AB0BEF1DBD

Biological materials
Mutant
BKE11770 (cotW::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGTTTTCACCTCGTCT,  downstream forward: _UP4_TAGCCAATCATAAAAAATAG
BKK11770 (cotW::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGTTTTCACCTCGTCT,  downstream forward: _UP4_TAGCCAATCATAAAAAATAG
References
Reviews
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Original Publications
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47669BC8073FB0F9799E06BB9FC39700F960910E

Page visits: 2831

Time of last update: 2025-04-08 20:19:45

Author of last update: Jstuelk