cotW
168
spore crust protein (insoluble fraction), formation of the spore crust
locus
BSU_11770
Molecular weight
12.20 kDa
pI
9.95
function
resistance of the spore
product
spore crust protein (insoluble fraction)
essential
no
synonyms
cotW
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5887 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,251,273 1,251,590
The protein
Structure
[AF|Q08310]
[wiki|Localization]
spore crust, localization depends on [protein|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX], [protein|B2636947990A303C43CEA8BFBE38811DD233A0A6|cotY], and [protein|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ] [Pubmed|23202530]
Expression and Regulation
Operons
genes
[gene|63870866AA2EA1727D77609B330FCD9704007679|cotV]-[gene|47669BC8073FB0F9799E06BB9FC39700F960910E|cotW]-[gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]
description
[Pubmed|7519271]
regulation
expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE], [wiki|SpoIIID]) [Pubmed|15383836]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|7519271,15383836], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,7519271], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
BKE11770 ([gene|47669BC8073FB0F9799E06BB9FC39700F960910E|cotW]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGTTTTCACCTCGTCT, downstream forward: _UP4_TAGCCAATCATAAAAAATAG
BKK11770 ([gene|47669BC8073FB0F9799E06BB9FC39700F960910E|cotW]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGTTTTCACCTCGTCT, downstream forward: _UP4_TAGCCAATCATAAAAAATAG
References
Reviews
Original Publications
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Time of last update: 2024-12-18 21:54:58
Author of last update: Jstuelk