cotX
168
spore crust protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat
locus
BSU_11760
Molecular weight
18.46 kDa
pI
4.23
function
spore crust assembly
product
spore crust protein (insoluble fraction)
essential
no
synonyms
cotX
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5886 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,250,656 1,251,174
The protein
Structure
[AF|Q08313]
Modification
contains a glycosylation motif [pubmed|31502725]
[wiki|Localization]
spore crust with a preference for spore poles [Pubmed|31502725,23202530]
Expression and Regulation
Operons
genes
[gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]
description
[Pubmed|7519271]
regulation
expressed late during sporulation ([wiki|SigE], [protein|search|SigK], [protein|search|GerE], [protein|search|GerR]) [Pubmed|26577401]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|7519271], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
[protein|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]: activation, [Pubmed|26577401], in [regulon|protein:0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, before [protein|63870866AA2EA1727D77609B330FCD9704007679|cotV] [Pubmed|26577401,15699190,7519271], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, before [protein|63870866AA2EA1727D77609B330FCD9704007679|cotV], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
genes
[gene|63870866AA2EA1727D77609B330FCD9704007679|cotV]-[gene|47669BC8073FB0F9799E06BB9FC39700F960910E|cotW]-[gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]
description
[Pubmed|7519271]
regulation
expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE], [wiki|SpoIIID]) [Pubmed|15383836]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|7519271,15383836], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,7519271], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
BKE11760 ([gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTATTCCTCCTTTTC, downstream forward: _UP4_TAGGACCTAAAAGCAGAGCT
BKK11760 ([gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTATTCCTCCTTTTC, downstream forward: _UP4_TAGGACCTAAAAGCAGAGCT
References
Reviews
Original Publications
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Time of last update: 2024-10-03 11:27:47
Author of last update: Jstuelk