cotX

cotX
168

spore crust protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat

locus
BSU_11760
Molecular weight
18.46 kDa
pI
4.23
Protein length
Gene length
function
spore crust assembly
product
spore crust protein (insoluble fraction)
essential
no
synonyms
cotX

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5886 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,250,656  1,251,174
The protein
Structure
[AF|Q08313]
Modification
contains a glycosylation motif [pubmed|31502725]
[wiki|Localization]
spore crust with a preference for spore poles [Pubmed|31502725,23202530]
Expression and Regulation
Operons
genes
[gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]
description
[Pubmed|7519271]
regulation
expressed late during sporulation ([wiki|SigE], [protein|search|SigK], [protein|search|GerE], [protein|search|GerR]) [Pubmed|26577401]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|7519271], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
[protein|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]: activation, [Pubmed|26577401], in [regulon|protein:0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, before [protein|63870866AA2EA1727D77609B330FCD9704007679|cotV] [Pubmed|26577401,15699190,7519271], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, before [protein|63870866AA2EA1727D77609B330FCD9704007679|cotV], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
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[gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]

2024-09-17 22:58:47

ghost

78

3ab0dc2db753765452db008eeb72f94a07034af0

552EFC63979CA8AFECC0CC5545AE6D831AB6DA46

genes
[gene|63870866AA2EA1727D77609B330FCD9704007679|cotV]-[gene|47669BC8073FB0F9799E06BB9FC39700F960910E|cotW]-[gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]
description
[Pubmed|7519271]
regulation
expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE], [wiki|SpoIIID]) [Pubmed|15383836]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|7519271,15383836], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,7519271], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
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[gene|63870866AA2EA1727D77609B330FCD9704007679|cotV]→[gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]

2024-09-28 05:02:35

ghost

55

d2c258d06ac9b622812dc5167b67f8b6cda6f5a0

A452B6601F16F2096F9BDD8987ADC1AB0BEF1DBD

Biological materials
Mutant
BKE11760 ([gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATCTATTCCTCCTTTTC,  downstream forward: _UP4_TAGGACCTAAAAGCAGAGCT
BKK11760 ([gene|905148CAF82018E7F8E800FDF3F41163AAA8E682|cotX]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATCTATTCCTCCTTTTC,  downstream forward: _UP4_TAGGACCTAAAAGCAGAGCT
References
Reviews
23202530,27227299
Original Publications
7519271,10788508,20451384,12107147,21665972,21821766,26821119,26577401,30582883,31502725,33596081

905148CAF82018E7F8E800FDF3F41163AAA8E682

Page visits: 3593

Time of last update: 2024-10-03 11:27:47

Author of last update: Jstuelk