gmuF

gmuF
168

mannose-6-P-isomerase

Locus
BSU_05870
Molecular weight
35.34 kDa
Isoelectric point
5.89
Protein length
315 aaSequenceBlast
Gene length
948 bpSequenceBlast
Function
glucomannan utilization
Product
mannose-6-P-isomerase
Essential
no
Synonyms
gmuF, ydhS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1482 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
631,808  632,755
The protein
Catalyzed reaction/ biological activity
D-mannose 6-phosphate --> D-fructose 6-phosphate (according to UniProt)
Protein family
mannose-6-phosphate isomerase type 1 family (with ManA and Pmi, according to UniProt)
Structure
1QWR (PDB) (Pmi, 58% identity)
O05511 (AlphaFold)
Paralogous protein(s)
Pmi, ManA
Expression and Regulation
Operons
Genes
gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
Description
PubMed
Regulation
induced by cellobiose (GmuR) PubMed
Regulatory mechanism
GmuR: repression, PubMed, in gmuR regulon
CcpA: repression, PubMed, in ccpA regulon
AbrB: activation, PubMed, in abrB regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

gmuB→gmuG

2025-03-16 15:57:23

Jstuelk

109

1716709ba10a9af523abc0d89eb44ea784dd12d9

42FBC6CD7712CC913DB98C4B417CB4A13C8FAE20

Biological materials
Mutant
MGNA-C194 (ydhS::erm), available at the NBRP B. subtilis, Japan
BKE05870 (gmuF::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AGGCTCTAAAAATAATGGAT,  downstream forward: _UP4_CCTTAATGAATGGGGGAGTT
BKK05870 (gmuF::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AGGCTCTAAAAATAATGGAT,  downstream forward: _UP4_CCTTAATGAATGGGGGAGTT
References
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35225776F6044513D3E77DBBD6A7A8FE976F506A

Page visits: 2791

Time of last update: 2025-04-02 20:03:12

Author of last update: Melvin.boenninger