Difference between revisions of "S-box Element"

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* In the aabsence of SAM, the [[riboswitch]] has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
 
* In the aabsence of SAM, the [[riboswitch]] has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
  
Genes controlled by S-box element:
+
==Genes controlled by a S-box==
 
* ''[[cysH]]-[[cysP]]-[[sat]]-[[cysC]]-[[ylnD]]-[[ylnE]]-[[ylnF]]''
 
* ''[[cysH]]-[[cysP]]-[[sat]]-[[cysC]]-[[ylnD]]-[[ylnE]]-[[ylnF]]''
 
* ''[[metE]]''
 
* ''[[metE]]''
 +
* ''[[metI]]''-''[[metC]]''
 
* ''[[metK]]''
 
* ''[[metK]]''
* ''[[yitJ]]-[[yitI]]-[[yitH]]''
+
* ''[[metN]]-[[metP]]-[[metQ]]''
* ''[[metI]]''-''[[metC]]''
 
 
* ''[[mtnK]]-[[mtnS]]''
 
* ''[[mtnK]]-[[mtnS]]''
 
* ''[[mtnW]]-[[mtnX]]-[[mtnB]]-[[mtnD]]''
 
* ''[[mtnW]]-[[mtnX]]-[[mtnB]]-[[mtnD]]''
* ''[[yoaD]]''
+
* ''[[yitJ]]-[[yitI]]-[[yitH]]''
* ''[[yusC]]''
+
* ''[[yoaD]]-[[yoaC]]-[[yoaB]]''
 
* ''[[yxjG]]''
 
* ''[[yxjG]]''
 
* ''[[yxjH]]''
 
* ''[[yxjH]]''

Revision as of 11:38, 7 June 2009

The S-box element is a riboswitch that controls different genes of sulphur metabolism in response to the presence of S-adenosylmethionine.

  • Upon binding of SAM, the riboswitch adopts a terminator structure resulting in transcription termination.
  • In the aabsence of SAM, the riboswitch has the antitermination structure that allows transcription elongation into the controlled gene/ operon.

Genes controlled by a S-box

References

Jerneja Tomsic, Brooke A McDaniel, Frank J Grundy, Tina M Henkin
Natural variability in S-adenosylmethionine (SAM)-dependent riboswitches: S-box elements in bacillus subtilis exhibit differential sensitivity to SAM In vivo and in vitro.
J Bacteriol: 2008, 190(3);823-33
[PubMed:18039762] [WorldCat.org] [DOI] (I p)

T M Henkin, F J Grundy
Sensing metabolic signals with nascent RNA transcripts: the T box and S box riboswitches as paradigms.
Cold Spring Harb Symp Quant Biol: 2006, 71;231-7
[PubMed:17381302] [WorldCat.org] [DOI] (P p)