Difference between revisions of "EpsM"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=epsM_3516233_3516883_-1 epsM] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=epsM_3516233_3516883_-1 epsM] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] {{PubMed|15661000}}
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15661000}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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<pubmed>20374491 20230605 </pubmed>
 
<pubmed>20374491 20230605 </pubmed>
 
===Other original publications===
 
===Other original publications===
'''Additional publications:''' {{PubMed|20817675}}
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<pubmed>22113911 15661000,16430695,18047568,18647168 20720312 20817675 21856853 21815947</pubmed>
<pubmed>22113911</pubmed>
 
<big>''Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J''  </big>
 
<big>'''RNA processing in ''Bacillus subtilis'': identification of targets of the essential RNase Y.''' </big>
 
<big>Mol Microbiol. 2011 81(6): 1459-1473. </big>
 
[http://www.ncbi.nlm.nih.gov/pubmed/21815947 PubMed:21815947]
 
 
 
<big>''Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J''  </big>
 
<big>'''A Novel Factor Controlling Bistability in ''Bacillus subtilis'': The YmdB Protein Affects</big>
 
<big>Flagellin Expression and Biofilm Formation.''' </big>
 
<big>J Bacteriol.: 2011, 193(21):5997-6007. </big>
 
[http://www.ncbi.nlm.nih.gov/pubmed/21856853 PubMed:21856853]
 
 
 
<pubmed>15661000,16430695,18047568,18647168 20720312</pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:45, 27 March 2013

  • Description: similar to serine O-acetyltransferase, extracellular polysaccharide synthesis

Gene name epsM
Synonyms yvfD
Essential no
Product unknown
Function biofilm formation
Gene expression levels in SubtiExpress: epsM
Regulation of this protein in SubtiPathways:
Biofilm
MW, pI 22 kDa, 9.427
Gene length, protein length 648 bp, 216 aa
Immediate neighbours epsN, epsL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvfD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
EpsM expression.png















Categories containing this gene/protein

biofilm formation

This gene is a member of the following regulons

AbrB regulon, EAR riboswitch, SinR regulon

The gene

Basic information

  • Locus tag: BSU34240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: transferase hexapeptide repeat family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References

Reviews

Original publications

The EAR RNA switch

Irnov Irnov, Wade C Winkler
A regulatory RNA required for antitermination of biofilm and capsular polysaccharide operons in Bacillales.
Mol Microbiol: 2010, 76(3);559-75
[PubMed:20374491] [WorldCat.org] [DOI] (I p)

Zasha Weinberg, Joy X Wang, Jarrod Bogue, Jingying Yang, Keith Corbino, Ryan H Moy, Ronald R Breaker
Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes.
Genome Biol: 2010, 11(3);R31
[PubMed:20230605] [WorldCat.org] [DOI] (I p)

Other original publications