Difference between revisions of "EpsA"

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(Extended information on the protein)
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* '''Additional information:'''  
 
* '''Additional information:'''  
 
** induction by sequestration of [[SinR]] by [[SinI]] or [[SlrA]] {{PubMed|15661000,19788541}} or by SlrR {{PubMed|20351052}}
 
** induction by sequestration of [[SinR]] by [[SinI]] or [[SlrA]] {{PubMed|15661000,19788541}} or by SlrR {{PubMed|20351052}}
 +
** the ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]'' operon is not expressed in ''[[rny]]'' and ''[[ymdB]]'' mutants {{PubMed|21856853,21815947}}
  
 
=Biological materials =
 
=Biological materials =
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==Original publications==
 
==Original publications==
 
'''Additional publications:''' {{PubMed|20817675}}
 
'''Additional publications:''' {{PubMed|20817675}}
 +
<big>''Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J''  </big>
 +
<big>'''A Novel Factor Controlling Bistability in ''Bacillus subtilis'': The YmdB Protein Affects</big>
 +
<big>Flagellin Expression and Biofilm Formation.''' </big>
 +
J Bacteriol. 2011 Aug 19. [Epub ahead of print]
 +
[http://www.ncbi.nlm.nih.gov/pubmed/21856853 PubMed:21856853]
 +
 +
<big>''Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J''  </big>
 +
<big>'''RNA processing in ''Bacillus subtilis'': identification of targets of the essential RNase Y.''' </big>
 +
<big>Mol Microbiol. 2011 Aug 4. doi: 10.1111/j.1365-2958.2011.07777.x. [Epub ahead of print] </big>
 +
[http://www.ncbi.nlm.nih.gov/pubmed/21815947 PubMed:21815947]
 +
<pubmed>18763711,19193632,17005971 19779461 19820159 20418391 20525796 20572937,21803996 21843271 </pubmed>
 
<pubmed>15661000,16430695,18047568,18647168 20351052 </pubmed>
 
<pubmed>15661000,16430695,18047568,18647168 20351052 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:32, 23 August 2011

  • Description: extracellular polysaccharide synthesis, putative transmembrane modulator of EpsB activity, might activate EpsB autophosphorylation and substrate phosphorylation

Gene name epsA
Synonyms yveK
Essential no
Product unknown
Function biofilm formation
Interactions involving this protein in SubtInteract: EpsA
Regulation of this protein in SubtiPathways:
Biofilm
MW, pI 25 kDa, 6.071
Gene length, protein length 702 bp, 234 aa
Immediate neighbours epsB, slrR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YveK context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

protein modification, biofilm formation, membrane proteins

This gene is a member of the following regulons

AbrB regulon, SinR regulon

The gene

Basic information

  • Locus tag: BSU34370

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cpsC/capA family (according to Swiss-Prot)
  • Paralogous protein(s): TkmA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References

Reviews


Original publications

Additional publications: PubMed

Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J  
A Novel Factor Controlling Bistability in Bacillus subtilis: The YmdB Protein Affects
Flagellin Expression and Biofilm Formation. 
J Bacteriol. 2011 Aug 19. [Epub ahead of print]
PubMed:21856853
Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 Aug 4. doi: 10.1111/j.1365-2958.2011.07777.x. [Epub ahead of print] 
PubMed:21815947