Difference between revisions of "SubtInteract"
| Line 20: | Line 20: | ||
=Protein complexes in ''B. subtilis''= | =Protein complexes in ''B. subtilis''= | ||
==Complexes in [[Cellular processes]]== | ==Complexes in [[Cellular processes]]== | ||
| − | === [[cell wall synthesis]] and [[cell shape]]: the [[cell wall | + | === [[cell wall synthesis]] and [[cell shape]]: the [[cell wall biosynthetic complex]]=== |
=== [[cell division]]: the [[divisome]]=== | === [[cell division]]: the [[divisome]]=== | ||
| Line 38: | Line 38: | ||
===spore [[germination]]: the [[germinosome]]=== | ===spore [[germination]]: the [[germinosome]]=== | ||
| − | + | =Suspected hub proteins potentially involved in a large number of interactions (as deduced from a Yeast two-hybrid analysis)= | |
* [[FruA]], [[SwrC]], [[XhlA]], [[YhaP]], [[YhgE]], [[YkcC]], [[YqfF]], [[CsbC]], [[CssS]], [[FliZ]], [[MreD]], [[PpsC]], [[RacA]], [[Smc]], [[YclI]], [[YdeL]], [[YdgH]], [[YdbI]], [[YesS]], [[YkoT]], [[YopZ]], [[YqbD]], [[YtdP]], [[YueB]], [[YwqJ]], [[YyxA]] | * [[FruA]], [[SwrC]], [[XhlA]], [[YhaP]], [[YhgE]], [[YkcC]], [[YqfF]], [[CsbC]], [[CssS]], [[FliZ]], [[MreD]], [[PpsC]], [[RacA]], [[Smc]], [[YclI]], [[YdeL]], [[YdgH]], [[YdbI]], [[YesS]], [[YkoT]], [[YopZ]], [[YqbD]], [[YtdP]], [[YueB]], [[YwqJ]], [[YyxA]] | ||
<pubmed> 21630458</pubmed> | <pubmed> 21630458</pubmed> | ||
| − | + | =Important publications= | |
<pubmed>20658969 18228443 18219467 17953394 15264234 14706816 12127457 11827824 11377797 11306254 10851163 10842303 18366733 10694888 2200717 2441660 20969605 15451506 </pubmed> | <pubmed>20658969 18228443 18219467 17953394 15264234 14706816 12127457 11827824 11377797 11306254 10851163 10842303 18366733 10694888 2200717 2441660 20969605 15451506 </pubmed> | ||
Revision as of 18:41, 10 July 2011
Protein-protein interactions are essential for many activities of any living cell. These interactions involve multi-protein complexes that take part in central processes such as DNA replication, transcription or translation. Protein-protein interactions may also be involved in a variety of regulatory events. Metabolic enzymes do often form transien complexes that represent a complete pathways. These complexes are called metabolon. Finally, many interactions may be of a transient nature.
Contents
- 1 Methods to detect protein-protein interactions
- 2 Visualization of protein-protein interactions in B. subtilis
- 3 Protein complexes in B. subtilis
- 4 Suspected hub proteins potentially involved in a large number of interactions (as deduced from a Yeast two-hybrid analysis)
- 5 Important publications
Methods to detect protein-protein interactions
- Yeast Two Hybrid System PubMed
- TAP-Tag purification PubMed
Attention: Each technique detects only about 33% of all interactions PubMed
Visualization of protein-protein interactions in B. subtilis
- interactive protein-protein interaction map
- the beta version of SubtInteract
Protein complexes in B. subtilis
Complexes in Cellular processes
cell wall synthesis and cell shape: the cell wall biosynthetic complex
cell division: the divisome
Complexes in Metabolism
the metabolons of glycolysis and the TCA cycle PubMed
Complexes in Information processing
DNA replication: the replisome
transcription: RNA polymerase
translation: the ribosome
synthesis of glutamyl-tRNA(Gln): the transamidosome (GatA-GatB-GatC)-GltX-trnS-Gln
RNA processing and degradation: the RNA degradosome
Complexes involved in Lifestyles
general stress response: the stressosome
DNA uptake: the pseudopilus PubMed
spore germination: the germinosome
Suspected hub proteins potentially involved in a large number of interactions (as deduced from a Yeast two-hybrid analysis)
- FruA, SwrC, XhlA, YhaP, YhgE, YkcC, YqfF, CsbC, CssS, FliZ, MreD, PpsC, RacA, Smc, YclI, YdeL, YdgH, YdbI, YesS, YkoT, YopZ, YqbD, YtdP, YueB, YwqJ, YyxA
Important publications
