Difference between revisions of "ABC transporters"
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* [[MetN]], [[MetP]], [[MetQ]]: uptake of methionine | * [[MetN]], [[MetP]], [[MetQ]]: uptake of methionine | ||
− | ==Uptake of | + | ==Uptake of nucleosides== |
* [[NupO]]-[[NupP]]-[[NupQ]]: uptake of guanosine | * [[NupO]]-[[NupP]]-[[NupQ]]: uptake of guanosine | ||
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* [[OpuBA]]-[[OpuBB]]-[[OpuBC]]-[[OpuBD]]: [[ABC transporter]] for choline | * [[OpuBA]]-[[OpuBB]]-[[OpuBC]]-[[OpuBD]]: [[ABC transporter]] for choline | ||
* [[OpuCA]]-[[OpuCB]]-[[OpuCC]]-[[OpuCD]]: [[ABC transporter]] for glycine betaine/ carnitine/ choline | * [[OpuCA]]-[[OpuCB]]-[[OpuCC]]-[[OpuCD]]: [[ABC transporter]] for glycine betaine/ carnitine/ choline | ||
+ | |||
+ | ==Uptake of cofactors== | ||
+ | * [[YvrA]]-[[YvrB]]-[[YvrC]]: uptake of cobalamin | ||
==[[Iron metabolism|Uptake of iron/ siderophores]]== | ==[[Iron metabolism|Uptake of iron/ siderophores]]== | ||
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* [[ZnuA]]-[[ZnuB]]-[[ZnuC]]: uptake of zinc | * [[ZnuA]]-[[ZnuB]]-[[ZnuC]]: uptake of zinc | ||
* [[YvgM]]-[[YvgL]]: uptake of molybdenum (probably) | * [[YvgM]]-[[YvgL]]: uptake of molybdenum (probably) | ||
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− | |||
− | |||
==ABC transporters of unknown function== | ==ABC transporters of unknown function== | ||
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* [[YtlC]]-[[YtlD]]-[[YtlA]] | * [[YtlC]]-[[YtlD]]-[[YtlA]] | ||
* ([[YtrB]]-[[YtrE]])-([[YtrC]]-[[YtrD]])-[[YtrF]] | * ([[YtrB]]-[[YtrE]])-([[YtrC]]-[[YtrD]])-[[YtrF]] | ||
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=Exporters= | =Exporters= | ||
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=Relevant publications= | =Relevant publications= | ||
− | <pubmed> 10092453 1282354 18535149 20497229 21665979 23106164 27273632</pubmed> | + | <pubmed> 10092453 1282354 18535149 20497229 21665979 23106164 27273632 ,32569521</pubmed> |
=Back to [[categories]]= | =Back to [[categories]]= |
Latest revision as of 08:34, 25 June 2020
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Neighbouring categories |
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Contents
- 1 Importers
- 2 Exporters
- 3 Regulatory ABC transporters
- 4 Relevant publications
- 5 Back to categories
Importers
Uptake of carbon sources
- YurJ-(FrlM-FrlN)-FrlO: uptake of aminosugars
- AraN, AraP, AraQ: uptake of α-1,5-arabinooligosaccharides
- CycB, GanP, GanQ: uptake of galactotriose
- MdxE, MdxF, MdxG: uptake of maltodextrin
- AmyC, AmyD, MsmE: uptake of melibiose (probably)
- RbsA, RbsB, RbsC, RbsD: uptake of ribose
- RhiL-RhiF-RhiG: uptake of rhamnose oligosaccharides
- YtcP-YtcQ-YteP: uptake of polygalacturonan and rhamnogalacturonan
ATPase subunit of multiple sugar transport systems
Uptake of amino acids
- ArtP, ArtQ, ArtR: uptake of arginine
- TcyJ, TcyK, TcyL, TcyM, TcyN: uptake of cystine
- TcyA, TcyB, TcyC: uptake of cystine
- YxeM-YxeN-YxeO: uptake of S-(2-succino)cysteine (putative)
- GlnH, GlnM, GlnP, GlnQ: uptake of glutamine
- MetN, MetP, MetQ: uptake of methionine
Uptake of nucleosides
Uptake of peptides
- AppA, AppB, AppC, AppD, AppF: uptake of oligopeptides
- DppB, DppC, DppD, DppE, YkfD: uptake of dipeptides
- OppA, OppB, OppC, OppD, OppF: uptake of oligopeptides
Uptake of compatible solutes for osmoprotection
- OpuAA-OpuAB-OpuAC: ABC transporter for glycine betaine
- OpuBA-OpuBB-OpuBC-OpuBD: ABC transporter for choline
- OpuCA-OpuCB-OpuCC-OpuCD: ABC transporter for glycine betaine/ carnitine/ choline
Uptake of cofactors
Uptake of iron/ siderophores
- YusV-FeuB-FeuC-FeuA: uptake of the siderophores enterobactin and bacillibactin
- FhuC-FhuB-FhuG-FhuD-YxeB: uptake of ferrichrome und ferrioxamine
- YclN-YclO-YclP-YclQ: uptake of petrobactin (a siderophore produced by B. anthracis and B. cereus)
- YusV-YfiZ-YfhA-YfiY: uptake of the siderophores schizokinen and arthrobactin
- YfmF-YfmD-YfmE-YfmC-YhfQ: uptake of iron/citrate
Uptake of ions
- MntB-MntA-MntC-MntD: uptake of manganese
- PstBA-PstBB-PstS-PstC-PstA: uptake of phosphate
- SsuA-SsuB-SsuC: uptake of aliphatic sulfonate
- ZnuA-ZnuB-ZnuC: uptake of zinc
- YvgM-YvgL: uptake of molybdenum (probably)
ABC transporters of unknown function
Exporters
Efflux of antibiotics
- VmlR: efflux of virginiamycin M and lincomycin
- BmrA: efflux of multiple antibiotics
- BmrC-BmrD: efflux of multiple antibiotics
- YfiL-YfiM-YfiN: probably efflux of linearmcin
Export of antibiotic substances
Export of peptides
- SkfE-SkfF: export of the spore killing factor
- YknY-YknZ
- BceA-BceB: export of bacitracin, plectasin, mersacidin and actagardine
- YxdL-YxdM
- PsdA-PsdB: export of lipid II-binding lantibiotics, such as nisin and gallidermin
- YxlF-YxlG
- YydI-YydJ: export of the modified YydF epipeptide, control of LiaR-LiaS activity
Export of cell wall components
Export of ions
Exporters of unknown function
- YfmM
- YfmR
- YgaD
- YhaQ-YhaP
- YhcG-YhcE
- YhcH-YhcI
- YknU-YknV
- YkpA
- YthP-YthQ
- YvfR-YvfS
- YvrO-YvrN
- YwjA
- YybJ-(YybK-YybL)
Regulatory ABC transporters
- CydC-CydD: required for expression of cytochrome bd
- EcsA-EcsB: regulation of the secretion apparatus and of intra-membrane proteolysis
- FtsE-FtsX: activation of Spo0A and initiation of sporulation
- BmrC-BmrD: involved in the signalling pathway to activate KinA at the onset of sporulation
- SufC: required for the synthesis of Fe-S clusters
Relevant publications
Christoph Thomas, Robert Tampé
Structural and Mechanistic Principles of ABC Transporters.
Annu Rev Biochem: 2020, 89;605-636
[PubMed:32569521]
[WorldCat.org]
[DOI]
(I p)
Kaspar P Locher
Mechanistic diversity in ATP-binding cassette (ABC) transporters.
Nat Struct Mol Biol: 2016, 23(6);487-93
[PubMed:27273632]
[WorldCat.org]
[DOI]
(I p)
Susanne Gebhard
ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation.
Mol Microbiol: 2012, 86(6);1295-317
[PubMed:23106164]
[WorldCat.org]
[DOI]
(I p)
Sebastian Dintner, Anna Staron, Evi Berchtold, Tobias Petri, Thorsten Mascher, Susanne Gebhard
Coevolution of ABC transporters and two-component regulatory systems as resistance modules against antimicrobial peptides in Firmicutes Bacteria.
J Bacteriol: 2011, 193(15);3851-62
[PubMed:21665979]
[WorldCat.org]
[DOI]
(I p)
Thomas Eitinger, Dmitry A Rodionov, Mathias Grote, Erwin Schneider
Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions.
FEMS Microbiol Rev: 2011, 35(1);3-67
[PubMed:20497229]
[WorldCat.org]
[DOI]
(I p)
Amy L Davidson, Elie Dassa, Cedric Orelle, Jue Chen
Structure, function, and evolution of bacterial ATP-binding cassette systems.
Microbiol Mol Biol Rev: 2008, 72(2);317-64, table of contents
[PubMed:18535149]
[WorldCat.org]
[DOI]
(I p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
C F Higgins
ABC transporters: from microorganisms to man.
Annu Rev Cell Biol: 1992, 8;67-113
[PubMed:1282354]
[WorldCat.org]
[DOI]
(P p)