Difference between revisions of "EpsI"

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{{SubtiWiki regulon|[[AbrB regulon]]}},
 
{{SubtiWiki regulon|[[AbrB regulon]]}},
 
{{SubtiWiki regulon|[[EAR riboswitch]]}},
 
{{SubtiWiki regulon|[[EAR riboswitch]]}},
 +
{{SubtiWiki regulon|[[RemA regulon]]}},
 
{{SubtiWiki regulon|[[SinR regulon]]}}
 
{{SubtiWiki regulon|[[SinR regulon]]}}
  
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[SinR]]: transcription repression {{PubMed|15661000}}
+
** [[SinR]]: transcription anti-activation (prevents binding of [[RemA]]) {{PubMed|23646920}}
 +
** [[RemA]]: transcription activation {{PubMed|23646920}}
 
** [[AbrB]]: transcription repression {{PubMed|20817675}}
 
** [[AbrB]]: transcription repression {{PubMed|20817675}}
  
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<pubmed>20374491 20230605 </pubmed>
 
<pubmed>20374491 20230605 </pubmed>
 
===Other original publications===
 
===Other original publications===
<pubmed>15661000,16430695,18047568,18647168 20720312 20817675 21856853 21815947</pubmed>
+
<pubmed>15661000,16430695,18047568,18647168 20720312 20817675 21856853 21815947 23646920</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:47, 24 May 2013

  • Description: extracellular polysaccharide synthesis

Gene name epsI
Synonyms yveS
Essential no
Product unknown
Function biofilm formation
Gene expression levels in SubtiExpress: epsI
Regulation of this protein in SubtiPathways:
Biofilm
MW, pI 41 kDa, 8.043
Gene length, protein length 1074 bp, 358 aa
Immediate neighbours epsJ, epsH
Sequences Protein DNA DNA_with_flanks
Genetic context
YveS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
EpsI expression.png















Categories containing this gene/protein

biofilm formation

This gene is a member of the following regulons

AbrB regulon, EAR riboswitch, RemA regulon, SinR regulon

The gene

Basic information

  • Locus tag: BSU34290

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: polysaccharide pyruvyl transferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References

Reviews

Original publications

The EAR RNA switch

Irnov Irnov, Wade C Winkler
A regulatory RNA required for antitermination of biofilm and capsular polysaccharide operons in Bacillales.
Mol Microbiol: 2010, 76(3);559-75
[PubMed:20374491] [WorldCat.org] [DOI] (I p)

Zasha Weinberg, Joy X Wang, Jarrod Bogue, Jingying Yang, Keith Corbino, Ryan H Moy, Ronald R Breaker
Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes.
Genome Biol: 2010, 11(3);R31
[PubMed:20230605] [WorldCat.org] [DOI] (I p)

Other original publications