Difference between revisions of "Response regulator aspartate phosphatases"
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* [[RapH]]: bifuntional protein: dephosphorylates [[Spo0F]]-P and inhibits the DNA-binding activity of [[ComA]]-P | * [[RapH]]: bifuntional protein: dephosphorylates [[Spo0F]]-P and inhibits the DNA-binding activity of [[ComA]]-P | ||
* [[RapI]], [[PhrI]]: [[RapI]] inhibits the DNA-binding activity of [[ImmR]] | * [[RapI]], [[PhrI]]: [[RapI]] inhibits the DNA-binding activity of [[ImmR]] | ||
| − | * [[RapJ]]: | + | * [[RapJ]]: dephosphorylates [[Spo0F]] |
* [[RapK]], [[PhrK]]: [[RapK]] inhibits the DNA-binding activity of [[ComA]]-P | * [[RapK]], [[PhrK]]: [[RapK]] inhibits the DNA-binding activity of [[ComA]]-P | ||
Revision as of 17:09, 27 March 2013
These proteins contain the so-called tetratricopeptide repeats (TPRs) protein-protein interaction module. They control the phosphorelay for sporulation initiation by dephosphorylating Spo0F-P or they inhibit transcription factors by protein-protein interaction (without affecting phosphorylation). The activity of these proteins can be controlled by small peptides that are expressed as precursors, exported, and re-imported into the cell.
The RAP proteins of B. subtilis, their cognate peptides and target proteins
- RapA, PhrA: RapA dephosphorylates Spo0F-P
- RapB: dephosphorylates Spo0F-P
- RapC, PhrC: RapC inhibits the DNA-binding activity of ComA-P
- RapD: RapD inhibits the DNA-binding activity of ComA-P
- RapE, PhrE: RapE dephosphorylates Spo0F-P
- RapF, PhrF: RapF inhibits the DNA-binding activity of ComA-P
- RapG, PhrG: RapG inhibits the DNA-binding activity of DegU-P
- RapH: bifuntional protein: dephosphorylates Spo0F-P and inhibits the DNA-binding activity of ComA-P
- RapI, PhrI: RapI inhibits the DNA-binding activity of ImmR
- RapJ: dephosphorylates Spo0F
- RapK, PhrK: RapK inhibits the DNA-binding activity of ComA-P
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