deoR

deoR
168

transcriptional repressor of the dra-nupC-pdp operon

Locus
BSU_39430
Molecular weight
35.10 kDa
Isoelectric point
6
Protein length
313 aaSequenceBlast
Gene length
942 bpSequenceBlast
Function
regulation of deoxyribonucleotide utilization
Product
transcriptional repressor
Essential
no
Synonyms
deoR, yxxC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2390 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,052,379 → 4,053,320
The protein
Catalyzed reaction/ biological activity
transcription repression of the dra-nupC-pdp operon
Protein family
SorC transcriptional regulatory family (with CggR, according to UniProt)
Domains
N-terminal DNA-binding domain PubMed
C-terminal effector binding domain PubMed
Structure
8R7Y (PDB) (complex with operator DNA) PubMed
4OQQ (PDB) (C-terminal effector binding domain) PubMed
7BHY (PDB) (complex of the DNA-binding domain with the operator DNA) PubMed
4OQP (C-terminal effector binding domain bound to the effector deoxyribose-5-P) PubMed
P39140 (AlphaFold)
Effectors of protein activity
deoxyribose-5-P acts as the molecular inducer PubMed
Expression and Regulation
Operons
Genes
deoR
Description
PubMed
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deoR

2025-04-04 02:09:03

ghost

116

0329b698241387249c8094455fc2617143f3f14b

6AC95F79C557792B4D2CB6DE2804F1FAFF574521

Biological materials
Mutant
BKE39430 (ΔdeoR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTGCACCTCCCTGTGG,  downstream forward: _UP4_TGACACGTTCAAACCTTTCA
BKK39430 (ΔdeoR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTGCACCTCCCTGTGG,  downstream forward: _UP4_TGACACGTTCAAACCTTTCA
References
Reviews
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Original Publications
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E9C4C569F18B3335DA9C7FB5B17C87D661E62669

Page visits: 4642

Time of last update: 2025-04-11 19:38:10

Author of last update: Jstuelk