ycbE
168
galactarate/glucarate transporter in (proton symport)
locus
BSU_02480
Molecular weight
49.09 kDa
pI
9.21
function
glucarate uptake
product
galactarate/glucarate transporter in (proton symport)
essential
no
synonyms
ycbE, gudP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2271 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
270,396 271,763
The protein
Protein family
[wiki|major facilitator superfamily] (according to UniProt)
Phthalate permease family (with [protein|6D08E897DD697523FD0720704A25AD4472075B6C|exuT] and [protein|41AB19B291C766E55CA1C5BAEF157FD26B5D4297|yybO], according to UniProt)
Structure
[PDB|6E9N] (from E. coli, 41.9% identity) [pubmed|31083648]
[AF|P42237]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|3542BC20C11985B3CFAA4F930E8D794700ADFD2E|ycbC]-[gene|5B66ADB81AB141982F187B1C5E3A9346AA064DE2|ycbD]-[gene|9C4932DA4DEF99263E57871A99684E3DAD93E1EC|ycbE]-[gene|372F2A420309DB0193AEF36A740EBA26410F97F2|ycbF]-[gene|1A65880F68898002EE8774F34EDC47F0243B7273|ycbG]-[gene|BA556E144975921DFDD598B0A7480C65176F0F14|ycbH]-[gene|349C99C258331962455100E2662DA2272E946C8A|ycbJ]
description
[Pubmed|12044674]
regulation
induced by D-glucarate/galactarate ([protein|search|YcbG]) [Pubmed|12044674]
regulatory mechanism
[protein|1A65880F68898002EE8774F34EDC47F0243B7273|ycbG]: repression, [Pubmed|12044674], in [regulon|protein:1A65880F68898002EE8774F34EDC47F0243B7273|ycbG regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|18840696], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
Biological materials
Mutant
MGNA-C028 (ycbE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2026 NBRP B. subtilis, Japan]
BKE02480 ([gene|9C4932DA4DEF99263E57871A99684E3DAD93E1EC|ycbE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTATCTTCTCCTTTTC, downstream forward: _UP4_TAATATTTATGAAAGCGCTT
BKK02480 ([gene|9C4932DA4DEF99263E57871A99684E3DAD93E1EC|ycbE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTATCTTCTCCTTTTC, downstream forward: _UP4_TAATATTTATGAAAGCGCTT
References
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Time of last update: 2024-11-20 19:54:55
Author of last update: Jstuelk