yhcY
168
two-component sensor kinase
locus
BSU_09320
Molecular weight
41.83 kDa
pI
6.64
function
unknown
product
two-component sensor kinase
essential
no
synonyms
yhcY
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4585 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,008,668 1,009,807
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of [protein|DD799ED3EB79457C27ED30C7B4DBBC2C8F962191|yhcZ] in a Asp residue
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
[wiki|Domains]
[wiki|Histidine kinase domain] (aa 185-373) (according to UniProt)
Structure
[AF|O07527]
Modification
autophosphorylation on a His residue
[wiki|Localization]
cytoplasm (Homogeneous) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|8D570AEE5D78A9A3CDBB1F457630BAF5DB59BCFD|yhcY]-[gene|DD799ED3EB79457C27ED30C7B4DBBC2C8F962191|yhcZ]-[gene|345EC248C0ADF48B0C25B175241AAE982E0E9B78|yhdA]
description
[Pubmed|16816187]
regulatory mechanism
[protein|49E70A20CC05DBE485953C0AE34E634EFB33C3B2|liaR]: activation, [Pubmed|16816187], in [regulon|protein:49E70A20CC05DBE485953C0AE34E634EFB33C3B2|liaR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|16816187], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A729 (yhcY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/729 NBRP B. subtilis, Japan]
BKE09320 ([gene|8D570AEE5D78A9A3CDBB1F457630BAF5DB59BCFD|yhcY]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTTCTCACTCCGGCAT, downstream forward: _UP4_AAAAGCCGAAAAGGAGGGGC
BKK09320 ([gene|8D570AEE5D78A9A3CDBB1F457630BAF5DB59BCFD|yhcY]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTTCTCACTCCGGCAT, downstream forward: _UP4_AAAAGCCGAAAAGGAGGGGC
References
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Time of last update: 2024-12-29 08:31:45
Author of last update: Melvin.boenninger