sdaAA
168
L-serine deaminase
locus
BSU_15860
Molecular weight
30.78 kDa
pI
4.87
function
serine utilization
product
L-serine deaminase (alpha chain)
essential
no
ec
4.3.1.17
synonyms
sdaAA, ylpA, sdaA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1760 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,658,930 1,659,832
Phenotypes of a mutant
delayed [wiki|biofilm formation] [pubmed|31138626]
overexpression of [gene|BC19D5B3764503298ED7136FC9F63A68F6AC464F|sdaAB]-[gene|8361D87307D2E8350945F592ABD24E2109E2E81A|sdaAA] results in resistance to serine [pubmed|32743959]
The protein
Catalyzed reaction/ biological activity
L-serine --> NH4+ + pyruvate (according to UniProt)
Protein family
iron-sulfur dependent L-serine dehydratase family (with [protein|BC19D5B3764503298ED7136FC9F63A68F6AC464F|sdaAB], according to UniProt)
[wiki|Cofactors]
Fe-S cluster [Pubmed|22686449]
Structure
[AF|O34607]
Expression and Regulation
Operons
genes
[gene|BC19D5B3764503298ED7136FC9F63A68F6AC464F|sdaAB]-[gene|8361D87307D2E8350945F592ABD24E2109E2E81A|sdaAA]-[gene|24B1C2A663A5B7C45940272595868F9F05A04A7B|recG]
description
[Pubmed|22383849]
Biological materials
Mutant
BKE15860 ([gene|8361D87307D2E8350945F592ABD24E2109E2E81A|sdaAA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAACTGGCTCCTCCTGAC, downstream forward: _UP4_ATTTTCGGAGGAGCGCTAGG
BKK15860 ([gene|8361D87307D2E8350945F592ABD24E2109E2E81A|sdaAA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAACTGGCTCCTCCTGAC, downstream forward: _UP4_ATTTTCGGAGGAGCGCTAGG
References
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Time of last update: 2024-11-08 13:45:51
Author of last update: Jstuelk