rplF

rplF
168

ribosomal protein uL6

Locus
BSU_01310
Molecular weight
19.37 kDa
Isoelectric point
9.92
Protein length
Gene length
Function
translation
Product
ribosomal protein L6 (uL6)
Essential
yes
Synonyms
rplF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0097 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
142,402  142,941
Phenotypes of a mutant
essential PubMed
The protein
Protein family
universal ribosomal protein uL6 family (single member, according to UniProt)
Structure
1RL6 (PDB) (Geobacillus stearothermophilus),  2R6A (PDB) (Geobacillus stearothermophilus),  2R6C (PDB)2R6D (PDB)2R6E (PDB)
Expression and Regulation
Operons
Description
Regulation
strongly repressed in response to glucose starvation in M9 medium PubMed
likely autorepression of operon expression upon binding of excess of one ribosomal protein to the untranslated region of the mRNA PubMed
expression is reduced in motile cells as compared to non-motile cells PubMed
Regulatory mechanism
stringent response: negative regulation, in stringent response
Sigma factors
SigA: sigma factor, PubMed (two promoters, about 140bp and 200bp upstream of the start codon), in sigA regulon
Additional information
term-seq has identified a potential novel regulatory RNA element (protein-dependent leader) including an intrinsic transcription terminator upstream of rpsJ PubMed
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rpsJrplQ

2025-04-02 13:05:40

Jstuelk

147

911D53E804EEFE6335D6A0F79722F9870F387CD3

9027854E648E8BF3E4A3C8492D350C69AC71C218

References
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Time of last update: 2025-04-04 10:35:30

Author of last update: Jstuelk