Iron metabolism

Parent categories	2. Metabolism 2.6. Additional metabolic pathways
Neighbouring categories	2.6.1. Biosynthesis of cell wall components 2.6.2. Biosynthesis of cofactors 2.6.3. Phosphate metabolism 2.6.4. Sulfur metabolism 2.6.5. Iron metabolism 2.6.6. Miscellaneous metabolic pathways
Related categories	Acquisition of iron Fur regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

Genes in this functional category

• Note: the main systems for iron uptake in B. subtilis 168 are YfmF-YfmD-YfmE-YfmC-YhfQ and EfeO-EfeU with EfeB PubMed

ABC transporters for theuptake of iron/ siderophores

• YusV-FeuB-FeuC-FeuA: uptake of the siderophores enterobactin and bacillibactin
• FhuC-FhuB-FhuG-FhuD-YxeB: uptake of ferrichrome und ferrioxamine
• YclN-YclO-YclP-YclQ: uptake of petrobactin (a siderophore produced by B. anthracis and B. cereus)
• YusV-YfiZ-YfhA-YfiY: uptake of the siderophores schizokinen and arthrobactin
• YfmF-YfmD-YfmE-YfmC-YhfQ: uptake of iron/citrate

Elemental iron transport system

• EfeO-EfeU, EfeB

Acquisition of iron/other

• besA
• btr
• cypX
• dhbA
• dhbB
• dhbC
• dhbE
• dhbF
• dps
• fbpA
• fbpB
• fbpC
• fsrA
• fur
• mrgA
• ybbA
• yhfQ
• ymfD
• yvmB
• yvmC

Acquisition of iron/ based on similarity

• ytoA
• yvrA
• yvrB
• yvrC

Export of Fe(II)

• pfeT

Biosynthesis of iron-sulfur clusters

• fra
• sufA
• sufB
• sufC
• sufD
• sufS
• sufU
• yitW

Key reviews

<pubmed> 20467446 16211402 12732309 23192658 25160631 26259870 26488283</pubmed>

Important original publications

<pubmed>27795321</pubmed>