LutP

• Description: lactate permease
  
  

Gene name	lutP
Synonyms	yvfH
Essential	no
Product	lactate permease
Function	lactate uptake
Gene expression levels in SubtiExpress: lutP
Metabolic function and regulation of this protein in SubtiPathways: lutP
MW, pI	59 kDa, 9.476
Gene length, protein length	1689 bp, 563 aa
Immediate neighbours	lutR, sigL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

ComA regulon

The gene

Basic information

• Locus tag: BSU34190

Phenotypes of a mutant

poor growth with lactate as single carbon source PubMed

Database entries

• BsubCyc: BSU34190

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: lactate uptake PubMed

• Protein family: lactate permease family (according to Swiss-Prot)

• Paralogous protein(s): LctP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • membrane PubMed

Database entries

• BsubCyc: BSU34190

• Structure:

• UniProt: P71067

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: lutP PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed at high cell density (ComA) PubMed

• Regulatory mechanism:
  • ComA: transcription activation (ComA) PubMed

• Additional information:
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 743 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage