SpoIVCA

• Description: site-specific DNA recombinase required for creating the sigK gene (excision of the skin element)
  
  

Gene name	spoIVCA
Synonyms	cisA
Essential	no
Product	site-specific DNA recombinase
Function	excision of the skin element, creation of the sigK gene
Gene expression levels in SubtiExpress: spoIVCA
MW, pI	57 kDa, 9.498
Gene length, protein length	1500 bp, 500 aa
Immediate neighbours	spoIVCB, arsC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination, sigma factors and their control, sporulation proteins, Skin element

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: BSU25770

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P17867

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoIVCA PubMed

• Expression browser: spoIVCA PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: