AzlB

• Description: transcriptional repressor of the azlB-azlC-azlD-brnQ-yrdK operon
  
  

Gene name	azlB
Synonyms	yrdG
Essential	no
Product	transcriptional repressor
Function	regulation of branched-chain amino acid transport
Gene expression levels in SubtiExpress: azlB
MW, pI	17 kDa, 4.867
Gene length, protein length	471 bp, 157 aa
Immediate neighbours	azlC, yrdF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, utilization of amino acids, transcription factors and their control, membrane proteins

This gene is a member of the following regulons

AzlB regulon

The AzlB regulon:

• azlB-azlC-azlD-brnQ-yrdK

The gene

Basic information

• Locus tag: BSU26720

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O07920

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: azlB-azlC-azlD-brnQ-yrdK PubMed

• Expression browser: azlB PubMed

• Sigma factor:

• Regulation: repressed by AzlB PubMed

• Regulatory mechanism: AzlB: transcriptional repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

B R Belitsky, M C Gustafsson, A L Sonenshein, C Von Wachenfeldt
An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport.
J Bacteriol: 1997, 179(17);5448-57
[PubMed:9287000] [WorldCat.org] [DOI] (P p)