Buk

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  • Description: butyrate kinase

Gene name buk
Synonyms yqiU, bkd
Essential no
Product butyrate kinase
Function utilization of branched-chain keto acids
Gene expression levels in SubtiExpress: buk
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis, Ile, Leu, Val
MW, pI 39 kDa, 5.466
Gene length, protein length 1089 bp, 363 aa
Immediate neighbours lpdV, bcd
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Buk context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Buk expression.png





























Categories containing this gene/protein

utilization of amino acids

This gene is a member of the following regulons

BkdR regulon, CodY regulon, SigL regulon

The gene

Basic information

  • Locus tag: BSU24070

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + butanoate = ADP + butanoyl phosphate (according to Swiss-Prot)
  • Protein family: acetokinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1X9J (from Thermotoga maritima, 52% identity, 69% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of isoleucine or valine (BkdR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References