ScoC

• Description: transcriptional repressor of genes expressed in the transition phase
  
  

Gene name	scoC
Synonyms	hpr, catA
Essential	no
Product	transcriptional repressor (MarR family)
Function	transition state regulator
MW, pI	23 kDa, 5.188
Gene length, protein length	609 bp, 203 aa
Immediate neighbours	yhaI, yhaH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU09990

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Genes controlled by ScoC

repressed: aprE, hag, flgM,

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: SinR-ScoC

• Localization:

Database entries

• Structure: 2FXA

• UniProt: P11065

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: scoC PubMed

• Sigma factor:

• Regulation:
  • expressed upon transition into the stationary phase (AbrB) PubMed

• Regulatory mechanism:
  • AbrB: transcription activation PubMed
  • SenS: positive regulation PubMed
  • SalA: negative regulation PubMed

• Additional information:

Biological materials

• Mutant: TMB081(tet), available in the Thorsten Mascher lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: