HrcA

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  • Description: transcriptional repressor of class I heat-shock genes

Gene name hrcA
Synonyms yqxE, yqeS
Essential no
Product transcriptional repressor
Function regulation of chaperone gene expression
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 38 kDa, 6.079
Gene length, protein length 1029 bp, 343 aa
Immediate neighbours grpE, hemN
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HrcA context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

transcription factors and their control, heat shock proteins

This gene is a member of the following regulons

HrcA regulon

The HrcA regulon:

The gene

Basic information

  • Locus tag: BSU25490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Protein family: hrcA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): GroEL acts as co-repressor
  • Effectors of protein activity:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Wolfgang Schumann, Bayreuth University, Germany Homepage

Thomas Wiegert, University of Bayreuth, Germany Homepage

Your additional remarks

References