CotX

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  • Description: spore coat protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat

Gene name cotX
Synonyms
Essential no
Product spore coat protein (insoluble fraction)
Function spore coat assembly
Gene expression levels in SubtiExpress: cotX
MW, pI 18 kDa, 4.228
Gene length, protein length 516 bp, 172 aa
Immediate neighbours cotY, cotW
Sequences Protein DNA DNA_with_flanks
Genetic context
CotX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotX expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU11760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

  • A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

cotX PubMed

before cotX: SigK PubMed

  • Regulation: repressed by casamino acids PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Peter T McKenney, Adam Driks, Patrick Eichenberger
The Bacillus subtilis endospore: assembly and functions of the multilayered coat.
Nat Rev Microbiol: 2013, 11(1);33-44
[PubMed:23202530] [WorldCat.org] [DOI] (I p)

Original publications