SpoIVCA

• Description: site-specific DNA recombinase required for creating the sigK gene (excision of the skin element)
  
  

Gene name	spoIVCA
Synonyms	cisA
Essential	no
Product	site-specific DNA recombinase
Function	excision of the skin element, creation of the sigK gene
MW, pI	57 kDa, 9.498
Gene length, protein length	1500 bp, 500 aa
Immediate neighbours	spoIVCB, arsC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

DNA repair/ recombination, sigma factors and their control, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: BSU25770

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P17867

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoIVCA PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: