SacC

From SubtiWiki
Revision as of 11:52, 21 July 2009 by Lflorez (talk | contribs)
Jump to: navigation, search
  • Description: levanase

Gene name sacC
Synonyms
Essential no
Product levanase
Function degradation of levan to fructose
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 75 kDa, 6.789
Gene length, protein length 2031 bp, 677 aa
Immediate neighbours yraA, levG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SacC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU27030

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolysis of terminal, non-reducing (2->1)- and (2->6)-linked beta-D-fructofuranose residues in fructans (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 32 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA) , carbon catabolite repression, induction by fructose
  • Regulatory mechanism: CcpA: transcription repression, catabolite repression: transcription repression by CcpA, transcription activator LevR is less active in the presence of glucose; induction: transcription activation by LevR
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References