Difference between revisions of "AcoA"

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** the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
 
** the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
 
** the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] {{PubMed|21815947}}
 
** the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] {{PubMed|21815947}}
 +
** number of protein molecules per cell (complex medium with amino acids, without glucose): 313 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 10:07, 17 April 2014

  • Description: acetoin dehydrogenase E1 component (TPP-dependent alpha subunit)

Gene name acoA
Synonyms yfjK
Essential no
Product acetoin dehydrogenase E1 component (TPP-dependent alpha subunit)
Function acetoin utilization
Gene expression levels in SubtiExpress: acoA
Interactions involving this protein in SubtInteract: AcoA
Metabolic function and regulation of this protein in SubtiPathways:
acoA
MW, pI 35 kDa, 4.912
Gene length, protein length 999 bp, 333 aa
Immediate neighbours yfjL, acoB
Sequences Protein DNA DNA_with_flanks
Genetic context
AcoA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AcoA expression.png















Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

AcoR regulon, CcpA regulon, SigL regulon

The gene

Basic information

  • Locus tag: BSU08060

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:
    • the mRNA is very stable (half-life > 15 min) PubMed
    • the mRNA is substantially stabilized upon depletion of RNase Y PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 313 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Michel Debarbouille, Pasteur Institute, Paris, France Homepage

Your additional remarks

References