Difference between revisions of "HrcA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of chaperone gene expression
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of chaperone gene expression
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25490 hrcA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25490 hrcA]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/HrcA HrcA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/HrcA HrcA]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[grpE]]'', ''[[hemN]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[grpE]]'', ''[[hemN]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14491&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25490 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:hrcA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:hrcA_context.gif]]

Revision as of 13:21, 13 May 2013

  • Description: transcriptional repressor of class I heat-shock genes

Gene name hrcA
Synonyms yqxE, yqeS
Essential no
Product transcriptional repressor
Function regulation of chaperone gene expression
Gene expression levels in SubtiExpress: hrcA
Interactions involving this protein in SubtInteract: HrcA
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 38 kDa, 6.079
Gene length, protein length 1029 bp, 343 aa
Immediate neighbours grpE, hemN
Sequences Protein DNA Advanced_DNA
Genetic context
HrcA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HrcA expression.png




























Categories containing this gene/protein

transcription factors and their control, heat shock proteins

This gene is a member of the following regulons

HrcA regulon

The HrcA regulon:

The gene

Basic information

  • Locus tag: BSU25490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Protein family: hrcA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): GroEL acts as co-repressor
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Wolfgang Schumann, Bayreuth University, Germany Homepage

Thomas Wiegert, University of Bayreuth, Germany Homepage

Your additional remarks

References