Difference between revisions of "BacC"
| Line 67: | Line 67: | ||
* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| − | ** oxidation of the C(7)-hydroxyl, penultimate step in | + | ** oxidation of the C(7)-hydroxyl, penultimate step in bacilysin biosynthesis {{PubMed|23317005}} |
* '''Protein family:''' short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot) | * '''Protein family:''' short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot) | ||
| Line 137: | Line 137: | ||
=References= | =References= | ||
| − | '''Additional publications:''' {{PubMed|12697329,21709425}} | + | '''Additional publications:''' {{PubMed|23317005,12697329,21709425}} |
| − | <pubmed>15609023 12372825, 21948839 19801406 | + | <pubmed>15609023 12372825, 21948839 19801406 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:35, 16 January 2013
- Description: bacilysin biosynthesis oxidoreductase
| Gene name | bacC |
| Synonyms | ywfD, ipa-82d |
| Essential | no |
| Product | bacilysin biosynthesis oxidoreductase |
| Function | biosynthesis of the antibiotic bacilysin |
| Gene expression levels in SubtiExpress: bacC | |
| MW, pI | 27 kDa, 4.959 |
| Gene length, protein length | 765 bp, 255 aa |
| Immediate neighbours | bacD, bacB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
AbrB regulon, CodY regulon, ScoC regulon
The gene
Basic information
- Locus tag: BSU37720
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- oxidation of the C(7)-hydroxyl, penultimate step in bacilysin biosynthesis PubMed
- Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39640
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Takashi Inaoka, Kozo Ochi
Scandium stimulates the production of amylase and bacilysin in Bacillus subtilis.
Appl Environ Microbiol: 2011, 77(22);8181-3
[PubMed:21948839]
[WorldCat.org]
[DOI]
(I p)
Takashi Inaoka, Guojun Wang, Kozo Ochi
ScoC regulates bacilysin production at the transcription level in Bacillus subtilis.
J Bacteriol: 2009, 191(23);7367-71
[PubMed:19801406]
[WorldCat.org]
[DOI]
(I p)
Gerhard Steinborn, Mohammad-Reza Hajirezaei, Jürgen Hofemeister
bac genes for recombinant bacilysin and anticapsin production in Bacillus host strains.
Arch Microbiol: 2005, 183(2);71-9
[PubMed:15609023]
[WorldCat.org]
[DOI]
(P p)
Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Kozo Ochi
Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.
J Biol Chem: 2003, 278(4);2169-76
[PubMed:12372825]
[WorldCat.org]
[DOI]
(P p)
