Difference between revisions of "BioD"
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* '''Operon:''' ''[[bioW]]-[[bioA]]-[[bioF]]-[[bioD]]-[[bioB]]-[[bioI]]-[[ytbQ]]'' {{PubMed|8763940,8892842}} | * '''Operon:''' ''[[bioW]]-[[bioA]]-[[bioF]]-[[bioD]]-[[bioB]]-[[bioI]]-[[ytbQ]]'' {{PubMed|8763940,8892842}} | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bioD_3091492_3092187_-1 bioD] {{PubMed|22383849}} |
| + | |||
| + | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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** [[BirA]]: transcription repression {{PubMed|8763940,8892842}} | ** [[BirA]]: transcription repression {{PubMed|8763940,8892842}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 15:41, 16 April 2012
- Description: dethiobiotin synthase
| Gene name | bioD |
| Synonyms | |
| Essential | no |
| Product | dethiobiotin synthase |
| Function | biosynthesis of biotin |
| Metabolic function and regulation of this protein in SubtiPathways: Biotin | |
| MW, pI | 25 kDa, 6.209 |
| Gene length, protein length | 693 bp, 231 aa |
| Immediate neighbours | bioB, bioF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30210
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin (according to Swiss-Prot)
- Protein family: dethiobiotin synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P53558
- KEGG entry: [3]
- E.C. number: 6.3.3.3
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews: PubMed
Original publications
J B Perkins, S Bower, C L Howitt, R R Yocum, J Pero
Identification and characterization of transcripts from the biotin biosynthetic operon of Bacillus subtilis.
J Bacteriol: 1996, 178(21);6361-5
[PubMed:8892842]
[WorldCat.org]
[DOI]
(P p)
S Bower, J B Perkins, R R Yocum, C L Howitt, P Rahaim, J Pero
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon.
J Bacteriol: 1996, 178(14);4122-30
[PubMed:8763940]
[WorldCat.org]
[DOI]
(P p)
