Difference between revisions of "SpoIVCA"
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| − | * '''Description:''' site-specific DNA recombinase required for creating the sigK gene (excision of the skin element) <br/><br/> | + | * '''Description:''' site-specific DNA recombinase required for creating the ''[[sigK]]'' gene (excision of the skin element) <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || site-specific DNA recombinase | |style="background:#ABCDEF;" align="center"| '''Product''' || site-specific DNA recombinase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || excision of the skin element, creation of the sigK gene | + | |style="background:#ABCDEF;" align="center"|'''Function''' || excision of the skin element, creation of the ''[[sigK]]'' gene |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.498 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.498 | ||
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''spoIVCA'' {{PubMed|2105293}} |
| − | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190,2105293}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed early during sporulation in the mother cell ([[SigE]], [[SpoIIID]]) {{PubMed|15699190,2105293,7966271}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SpoIIID]]: transcription activation {{PubMed|7966271}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 122: | ||
=References= | =References= | ||
| − | <pubmed>2163341,2105293,2841290,, </pubmed> | + | <pubmed>2163341,2105293,2841290,7966271, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:03, 24 November 2009
- Description: site-specific DNA recombinase required for creating the sigK gene (excision of the skin element)
| Gene name | spoIVCA |
| Synonyms | cisA |
| Essential | no |
| Product | site-specific DNA recombinase |
| Function | excision of the skin element, creation of the sigK gene |
| MW, pI | 57 kDa, 9.498 |
| Gene length, protein length | 1500 bp, 500 aa |
| Immediate neighbours | spoIVCB, arsC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU25770
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P17867
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spoIVCA PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
R Halberg, L Kroos
Sporulation regulatory protein SpoIIID from Bacillus subtilis activates and represses transcription by both mother-cell-specific forms of RNA polymerase.
J Mol Biol: 1994, 243(3);425-36
[PubMed:7966271]
[WorldCat.org]
[DOI]
(P p)
B Kunkel, R Losick, P Stragier
The Bacillus subtilis gene for the development transcription factor sigma K is generated by excision of a dispensable DNA element containing a sporulation recombinase gene.
Genes Dev: 1990, 4(4);525-35
[PubMed:2163341]
[WorldCat.org]
[DOI]
(P p)
T Sato, Y Samori, Y Kobayashi
The cisA cistron of Bacillus subtilis sporulation gene spoIVC encodes a protein homologous to a site-specific recombinase.
J Bacteriol: 1990, 172(2);1092-8
[PubMed:2105293]
[WorldCat.org]
[DOI]
(P p)
B Kunkel, K Sandman, S Panzer, P Youngman, R Losick
The promoter for a sporulation gene in the spoIVC locus of Bacillus subtilis and its use in studies of temporal and spatial control of gene expression.
J Bacteriol: 1988, 170(8);3513-22
[PubMed:2841290]
[WorldCat.org]
[DOI]
(P p)
