Difference between revisions of "Spo0A"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1QMP 1QMP] (with phosphorylated aspartate, Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=1FC3 1FC3] (trans-activation domain, Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=1LQ1 1LQ1] (complex with DNA) | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1QMP 1QMP] (with phosphorylated aspartate, ''Geobacillus stearothermophilus''), [http://www.rcsb.org/pdb/explore.do?structureId=1FC3 1FC3] (trans-activation domain, ''Geobacillus stearothermophilus''), [http://www.rcsb.org/pdb/explore.do?structureId=1LQ1 1LQ1] (complex with DNA) |
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P06534 P06534] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P06534 P06534] | ||
Revision as of 19:53, 28 May 2009
- Description: two-component response regulator, initiation of sporulation
| Gene name | spo0A |
| Synonyms | spo0C, spo0G, spoIIL, sof-1 |
| Essential | no |
| Product | two-component response regulator |
| Function | initiation of sporulation |
| MW, pI | 29 kDa, 5.989 |
| Gene length, protein length | 801 bp, 267 aa |
| Immediate neighbours | yqiG, spoIVB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Genes controlled by Spo0A
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 1QMP (with phosphorylated aspartate, Geobacillus stearothermophilus), 1FC3 (trans-activation domain, Geobacillus stearothermophilus), 1LQ1 (complex with DNA)
- Swiss prot entry: P06534
- KEGG entry: BSU24220
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Tony Wilkinson, York University, U.K. homepage
Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage
Your additional remarks
References
Virginia Castilla-Llorente, Margarita Salas, Wilfried J J Meijer
Different responses to Spo0A-mediated suppression of the related Bacillus subtilis phages Nf and phi29.
Environ Microbiol: 2009, 11(5);1137-49
[PubMed:19207565]
[WorldCat.org]
[DOI]
(I p)
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
