Difference between revisions of "PdxS"

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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
**  [[PdxS]]-[[PdxT]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16030023 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/14762015 PubMed2]
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**  [[PdxS]]-[[PdxT]] {{PubMed|25473090,14762015,16030023,17159152}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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=References=
 
=References=
  
<pubmed>15911615,14762015,,14651647, 17726680, 16493705, 16030023, 19152323,17159152 22517742 15378759</pubmed>
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<pubmed>15911615,14762015,25473090,14651647, 17726680, 16493705, 16030023, 19152323,17159152 22517742 15378759</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 09:26, 5 December 2014

  • Description: pyridoxal-5'-phosphate synthase (synthase domain)

Gene name pdxS
Synonyms yaaD
Essential no
Product pyridoxal-5'-phosphate synthase (synthase domain)
Function pyridoxal-5'-phosphate biosynthesis
Gene expression levels in SubtiExpress: pdxS
Interactions involving this protein in SubtInteract: PdxS
Metabolic function and regulation of this protein in SubtiPathways:
PdxS
MW, pI 31 kDa, 5.085
Gene length, protein length 882 bp, 294 aa
Immediate neighbours dacA, pdxT
Sequences Protein DNA DNA_with_flanks
Genetic context
YaaD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PdxS expression.png















Categories containing this gene/protein

biosynthesis of cofactors, phosphoproteins, most abundant proteins

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU00110

Phenotypes of a mutant

auxotrophic for pyridoxal 5'-phosphate PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: pdxS/SNZ family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: negatively controlled by Spo0A PubMed
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:
    • belongs to the 100 most abundant proteins PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 6001 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 16290 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 7634 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 4624 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 7523 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References