Difference between revisions of "BkdAA"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU24050&redirect=T BSU24050] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ptb-bcd-buk-lpdV-bkdAABB.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ptb-bcd-buk-lpdV-bkdAABB.html] | ||
| Line 93: | Line 94: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU24050&redirect=T BSU24050] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=1UMB 1UMB] (from '' Thermus thermophilus'', 42% identity, 57% similarity) {{PubMed|15033367}} | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=1UMB 1UMB] (from '' Thermus thermophilus'', 42% identity, 57% similarity) {{PubMed|15033367}} | ||
Revision as of 14:09, 2 April 2014
- Description: 2-oxoisovalerate dehydrogenase (E1 alpha subunit)
| Gene name | bkdAA |
| Synonyms | bfmBAA, bfmB1a, bkd |
| Essential | no |
| Product | 2-oxoisovalerate dehydrogenase (E1 alpha subunit) |
| Function | utilization of branched-chain keto acids |
| Gene expression levels in SubtiExpress: bkdAA | |
| Metabolic function and regulation of this protein in SubtiPathways: bkdAA | |
| MW, pI | 36 kDa, 4.778 |
| Gene length, protein length | 990 bp, 330 aa |
| Immediate neighbours | bkdAB, lpdV |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
BkdR regulon, CodY regulon, SigL regulon
The gene
Basic information
- Locus tag: BSU24050
Phenotypes of a mutant
Database entries
- BsubCyc: BSU24050
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 (according to Swiss-Prot)
- Protein family: BCKDHA family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: Membrane-proximal (Spotty) PubMed
Database entries
- BsubCyc: BSU24050
- UniProt: P37940
- KEGG entry: [3]
- E.C. number: 1.2.4.4
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
